Publications by authors named "Saboor -"

Folic acid (FA) plays a crucial role in various biological processes. Insufficient intake of FA during pregnancy can lead to serious clinical complications, including neural tube defect. The current study sought to assess the awareness, knowledge, and usage of FA among young females in Jazan region of Saudi Arabia.

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Purpose: Multiple sclerosis (MS) is a neurological disorder affecting almost 2.8 million people globally, approximately 80-85% of whom have the relapsing-remitting form of the disease (RRMS). There are several autoinjectors available for the administration of injectable disease-modifying therapies for the treatment of MS.

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The premise of extreme value theory focuses on the stochastic behaviour and occurrence of extreme observations in an event that is random. Traditionally for univariate case, the behaviour of the maxima is described either by the types-I, types-II or types-III extreme value distributions, primarily known as the Gumbel, Fréchet or reversed Weibull models. These are all particular cases of the generalized extreme value ( ) model.

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  • Anemia is a major public health issue in developing countries like Sudan, particularly affecting children who face serious health risks as a result.
  • A systematic review and meta-analysis of studies from various databases revealed that 53.5% of Sudanese children are affected by anemia, with various types identified including iron deficiency and sickle cell anemia.
  • The prevalence of anemia in Sudanese children has been increasing over the last 21 years, necessitating urgent action to address and mitigate this growing health concern.
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  • The study examines the link between JAK2 mutations and unusual venous thrombosis in young individuals living at high altitudes in Saudi Arabia, highlighting the significant health risks associated with myeloproliferative neoplasms.
  • Data was collected from two hospitals over three years, revealing that out of 208 JAK2 tests, only 40 were related to thrombotic events, with a low incidence of JAK2 mutations (5% of participants).
  • The findings suggest that while JAK2 mutations may be relevant for certain types of thrombosis, their routine testing for other cases, especially when blood counts are normal, may not be justified, indicating a need for further research.
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Anemia, particularly iron deficiency anemia (IDA), is a prevalent health issue globally and in Saudi Arabia, especially among young adult females. This study investigates the association between anemia and academic achievement among female students at the Female Health Campus of Jazan University, Jazan, Saudi Arabia. This cross-sectional study included 118 randomly selected participants aged 18-22.

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  • This paper introduces a new two-parameter unit probability model that generalizes the Kumaraswami distribution, offering more flexibility in its hazard and density functions compared to existing distributions.
  • It conducts a thorough analysis of the model's statistical features, including moments and order statistics, and provides explicit formulas for these.
  • The model's parameters are estimated using maximum likelihood estimation, with simulations showing its reliability, and its effectiveness is validated through application to four real data sets, highlighting its potential for diverse analytical use across various fields.
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Background: The rising prevalence of mental health issues in children, adolescents, and young adults has become an escalating public health issue, impacting approximately 10%-20% of young people on a global scale. Positive psychology interventions (PPIs) can act as powerful mental health promotion tools to reach wide-ranging audiences that might otherwise be challenging to access. This increased access would enable prevention of mental disorders and promotion of widespread well-being by enhancing self-efficacy, thereby supporting the achievement of tangible objectives.

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  • Erythroferrone (ERFE) is crucial in iron metabolism and influences several hematologic disorders, highlighting its importance in conditions like β-thalassemia and myelodysplastic syndromes.
  • Dysregulation of ERFE contributes to anemia and iron overload, making it a promising therapeutic target for various iron-related diseases.
  • Ongoing research into ERFE's role in chronic kidney disease and other conditions suggests that modulating its activity could lead to new treatments, emphasizing its potential in improving patient outcomes in hematology.
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Introduction: In the evolving healthcare landscape, we aim to integrate hyperspectral imaging into Hybrid Health Care Units to advance the diagnosis of medical diseases through the effective fusion of cutting-edge technology. The scarcity of medical hyperspectral data limits the use of hyperspectral imaging in disease classification.

Methods: Our study innovatively integrates hyperspectral imaging to characterize tumor tissues across diverse body locations, employing the Sharpened Cosine Similarity framework for tumor classification and subsequent healthcare recommendation.

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The most prevalent paediatric vision-threatening medical condition, retinoblastoma (RB), has been a global concern for a long time. Several conventional therapies, such as systemic chemotherapy and focal therapy, have been used for curative purposes; however, the search for tumour eradication with the least impact on surrounding tissues is still ongoing. This review focuses on the genetic origin, classification, conventional treatment modalities, and their combination with nano-scale delivery systems for active tumour targeting.

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Objectives: This study aimed to qualitatively explore (1) the experiences of female survivors of domestic abuse and mental health problems in Afghanistan; (2) how female survivors of violence and abuse, male members of the community and service providers perceive and respond to mental health and domestic violence in Afghanistan and (3) the provision of mental health services for female survivors of violence and abuse in Afghanistan, including the barriers and challenges faced around accessing mental health services.

Design: Qualitative interviews and framework thematic analysis.

Setting: Kabul, Bamyan and Nangarhar in Afghanistan.

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  • * Natural compounds found in various plants and marine life show promise in reducing neurodegeneration and improving cognitive function in research models.
  • * Combining these natural substances with nanotechnology, such as nanoparticles, can enhance their effectiveness and targeting ability for treating neurodegenerative disorders.
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  • Autism spectrum disorder (ASD) is characterized by challenges in social communication and repetitive behaviors, often linked with cognitive limitations.
  • Over the years, numerous studies, particularly using preclinical rat models, have explored the environmental and genetic influences on the development of ASD.
  • Recent findings highlight the endocannabinoid system’s role in ASD, suggesting it may influence metabolic and immune pathways, and present promising opportunities for targeted interventions based on preclinical rodent studies showing ASD-like symptoms from ECS manipulation.
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Background: Neurosurgery has 1 of the highest risks for medical malpractice claims. We reviewed the factors associated with neurosurgical malpractice claims and litigation in the United States and reported the outcomes through a systematic review of the literature.

Methods: We conducted a systematic review of the literature according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines using the Medline, Embase, Cochrane, PubMed, and Google Scholar databases.

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  • The research explores optimizing soybean biofuel blends for urban medium-duty commercial vehicles, focusing on production, economics, and engine performance.
  • An AI-driven analysis predicts combustion and emission characteristics, highlighting a decrease in brake thermal efficiency (BTE) and an increase in brake-specific fuel consumption (BSFC) when comparing diesel to biofuel blends.
  • The study finds that biofuel-diesel blends significantly reduce maximum cylinder pressure and emissions, improving engine performance and lowering exhaust pollutants.
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The critical impact of sodium-doped molybdenum (MoNa) in shaping the MoSe interfacial layer, influencing the electrical properties of CIGSe/Mo heterostructures, and achieving optimal MoSe formation conditions, leading to improved hetero-contact quality. Notably, samples with a 600-nm-thick MoNa layer demonstrate the highest resistivity (73 μΩcm) and sheet resistance (0.45 Ω/square), highlighting the substantial impact of MoNa layer thickness on electrical conductivity.

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This research explores the use of gated recurrent units (GRUs) for automated brain tumor detection using MRI data. The GRU model captures sequential patterns and considers spatial information within individual MRI images and the temporal evolution of lesion characteristics. The proposed approach improves the accuracy of tumor detection using MRI images.

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  • This study looks at how some bacteria become resistant to drugs by forming biofilms, which is a problem for infections that happen in hospitals.* -
  • Researchers found new strong inhibitors for a protein called LasR that helps bacteria form biofilms and cause illness, using special chemical compounds.* -
  • They used different scientific methods to understand how well these new compounds work and to see that one specific compound works best at stopping the LasR protein.*
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Background: Nutritional anemia is a significant public health concern worldwide, particularly affecting young adults and children in Saudi Arabia, where inadequate nutrition is considered a primary contributing factor. This study aims to (i) examine the levels of serum iron, folate, and vitamin B in young adult students, with a focus on identifying any deficiencies and their association with anemia; (ii) explore the prevalence of mixed-deficiency anemia resulting from deficiencies in serum iron, folate, and vitamin B (iii) explore how sociodemographic characteristics and dietary habits influence serum iron, folate, and vitamin B levels.

Materials And Methods: This cross-sectional study encompassed 158 young adult students at Jazan University, Saudi Arabia.

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  • Recent research has focused on the development of thiadiazole-based drugs that could be effective against diabetes, urease-related issues, and drug-resistant infections.
  • The study reports the creation of new derivatives starting from 4-(trifluoromethyl)benzoic acid, which were then tested for their biological effects.
  • Certain compounds displayed strong inhibitory activities, attributed to the presence of specific chemical groups that enhance their effectiveness, suggesting potential for further drug optimization.
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Background: Addiction disorders pose significant challenges to public health, necessitating innovative treatments. This assesses deep brain stimulation (DBS) as a potential intervention for addiction disorders.

Methods: A literature review was carried out with a focus on the role of DBS in addiction disorders and its future implications in neurosurgical research.

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Antithrombin is an essential protein that acts as a natural anticoagulant in the human body. It is synthesized by the liver and belongs to the serine protease inhibitors, which are commonly referred to as the SERPINS superfamily. The antithrombin molecule comprises 432 amino acids and has a molecular weight of approximately 58 200 D.

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