Publications by authors named "Sable Sharpley"
Meningitis confirmation in Burkina Faso uses PCR for detecting Streptococcus pneumoniae, Neisseria meningitidis, or Hemophilus influenzae. We identified 38 cases of meningitis among 590 that were PCR-positive for 3 nonpneumococcal streptococcal pathogens, including 21 cases of Streptococcus suis. Among the country's 13 regions, 10 had S.
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- Pneumococcal meningitis in the African meningitis belt is mainly caused by Streptococcus pneumoniae serotype 1, which is targeted by the 13-valent pneumococcal conjugate vaccine (PCV13) introduced in Niger in 2014.
- A study analyzing data from a national reference laboratory showed a significant decline in vaccine-type (VT) serotypes of S. pneumoniae in children under 5 years after the introduction of PCV13, from 74.0% to 28.1%.
- Despite the overall reduction in VT cases, serotype 1 continues to be the most prevalent cause of pneumococcal meningitis in older children and adults, highlighting the need for