Publications by authors named "Sabitha Thummala"
J Lab Physicians
September 2022
Article Synopsis
- Oxidative stress occurs when there’s an imbalance between oxidants and antioxidants, leading to the release of reactive oxygen species (ROS) that can damage vascular functions, with Cyclophilin A (CypA) enhancing these damaging effects in cardiovascular diseases.
- A study of 103 adults, 73 with coronary artery disease (CAD), measured serum levels of CypA and other biomarkers, revealing significantly higher levels in CAD patients compared to controls, and established correlations between CypA and inflammation markers.
- Results indicated that CypA and hsCRP levels can be used as potential indicators for CAD severity, showing high sensitivity and specificity at certain cut-off values, suggesting their relevance in diagnosing and understanding the
