Feasibility and reliability of clinical coding surveillance for the routine monitoring of adverse drug events in New Zealand hospitals.

Aim: To explore the feasibility and reliability of Clinical Coding Surveillance (CCS) for the routine monitoring of Adverse Drug Events (ADE) and describe the characteristics of harm identified through this approach in a large district health board (DHB).

Method: All hospital admissions at Waitemata DHB from 2015 to 2016 with an ADE-related ICD10-AM code of Y40-Y59, X40-X49 or T36-T50 were extracted from clinical coded data. The data was analysed using descriptive statistics, statistical process control and Pareto charts.

Surface plasmon assisted optical nonlinearities of uniformly oriented metal nano-ellipsoids in glass.

The nonlinear optical properties of nanocomposites consisting of non-spherical silver nanoparticles in glass matrix have been studied using the femtosecond Z-scan technique. The spheroidal nanoparticles were uniformly oriented along a common direction. By polarization sensitive studies, longitudinal and transverse plasmon resonances can be addressed separately.

Directionally selective optical limiting of femtosecond pulses in simple transparent two-layer systems.

Directionally selective nonlinear transmission behavior has been observed for simple glass-based two-layer systems in Z-scan experiments employing femtosecond pulses at a wavelength of λ=800 nm. Glass sheets of 1 mm thickness with a very thin surface layer (~2 μm) containing spherical Ag nanoparticles have been studied. In these samples, irradiating from the substrate side causes a strong transmission decrease via self-focusing of the beam and subsequent two-photon absorption in the thin layer, whereas the reverse direction may pass the sample without loss.