Assessing impaired gastric accommodation in children with functional constipation using the water load test.

Background: This study aimed to evaluate gastric accommodation in pediatric patients with functional constipation using the water load test.

Method: This was a cross-sectional case-control study. Herein, the water load test results of children aged >4 years with functional constipation referred to a Pediatric Gastroenterology Outpatient Clinic (functional constipation group) were compared with those of a control group (without functional constipation or chronic abdominal pain) recruited from two public schools.

Hypohydration, Functional Constipation, and Physical Activity in Elementary School Students.

This school-based, cross-sectional study aimed to evaluate whether hypohydration is related to functional constipation and physical activity in school-aged children. The study included 452 students aged 6-12 years. Hypohydration, defined as urinary osmolality >800 mOsm/kg, was more prevalent ( P = 0.

Overweight status, abdominal circumference, physical activity, and functional constipation in children.

Objective: The aim of this study was to assess the prevalence of functional constipation and its relationship with the food intake, overweight status, and physical activity of children.

Methods: This cross-sectional study included students from two public schools in the municipality of Osasco, which is located in the metropolitan area of São Paulo. Functional constipation was diagnosed if the clinical manifestations of the Rome IV criteria were present for more than 2 months.

Fluid intake and urinary osmolality in pediatric patients with functional constipation.

Purpose: This study aimed to evaluate fluid intake and urinary osmolality in pediatric patients with functional constipation.

Methods: This was a cross-sectional, case-control study that prospectively included two groups: 36 pediatric patients older than 4 years with functional constipation (Rome III criteria) who were consecutively admitted in a public tertiary pediatric gastroenterology outpatient clinic and 93 controls with normal bowel habits. The control group was recruited from a public school and did not have any of the characteristics of the Rome III criteria.

Prevalence of voluntary dehydration according to urine osmolarity in elementary school students in the metropolitan region of São Paulo, Brazil.

Objectives: To evaluate the prevalence of voluntary dehydration based on urine osmolarity in elementary school students from two public educational institutions in the metropolitan region of São Paulo and evaluate whether there is a relationship between voluntary dehydration and nutritional status or socioeconomic status.

Methods: Analytical cross-sectional study with students from two public schools in the city of Osasco. The determination of urine osmolarity was performed using the freezing method of the Advanced® Osmometer Model 3W2.

Water and fluid intake in the prevention and treatment of functional constipation in children and adolescents: is there evidence?

Objective: To study the evidence on the role of water and fluid intake in the prevention and treatment of functional intestinal constipation in children and adolescents.

Source Of Data: A search was carried out in the Medline database (between 1966 and 2016) for all published articles containing the following words: constipation, water, and fluids, published in Portuguese, English, and Spanish. All original articles that assessed children and adolescents were selected by title and abstract.

Behavioural changes observed in demyelination model shares similarities with white matter abnormalities in humans.

Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating disease of the central nervous system (CNS). Further to the symptoms resulting from demyelination, new studies point to the involvement of neuroinflammation and white matter abnormalities in psychiatric disorders and neurodegenerative diseases. Cuprizone, a model of MS, produces consistent demyelination and elicits behavioural, morphological and inflammatory changes in animals that share some similarities with those observed in humans.