Publications by authors named "Sabine L A G Vrancken"
Article Synopsis
- - The study aimed to evaluate the need for exchange transfusions in neonatal care, track the use and waste of transfusion products, and understand their prevalence across the Netherlands.
- - Data from all 9 neonatal intensive care units and 15 other hospitals were analyzed over an 11-year period, revealing that severe immune hemolysis was the most common reason for transfusions while around 50% of products ordered were not used.
- - The findings showed that only 14.6 out of every 100,000 liveborn neonates required an exchange transfusion, indicating that these procedures are quite rare in the Netherlands and a significant number of products go unused.
Aims: Management of kaposiform haemangioendotheliomas (KHE) with Kasabach-Merritt phenomenon is challenging in young infants who are subjected to developmental pharmacokinetic changes. Sirolimus, sometimes combined with corticosteroids, can be used as an effective treatment of KHE. Simultaneously, toxicities such as interstitial pneumonitis related to the use of sirolimus may be fatal.
View Article and Find Full Text PDFWe describe here the case of a boy who presented 2 days after birth with purpura fulminans on his feet and scalp. Laboratory investigations revealed signs of disseminated intravascular coagulation. An underlying coagulation disorder was suspected, and therapy with recombinant tissue plasminogen activator, fresh-frozen plasma, and unfractionated heparin was started.
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