[Termination of pregnancy in the 2nd trimester: mifepriston/misoprostol preferable to sulprostone].

Objective: To compare the efficacy of sulprostone and mifepristone/misoprostol when used for termination of pregnancy (TOP) in the 2nd trimester.

Design: Comparative retrospective cohort study.

Method: Data were collected on all women whose pregnancies were terminated in the 2nd trimester, in the presence of severe fetal defects, between 1996 and 2007 at the Radboud University Nijmegen Medical Centre, the Netherlands.