Publications by authors named "Sabine E I van der Laan"
Importance: Atherogenesis starts during childhood, making childhood and adolescence an important window of opportunity to prevent atherosclerotic cardiovascular disease later in life.
Objective: To identify early-life risk factors for preclinical atherosclerosis in adolescence.
Design, Setting, And Participants: This cohort study is part of the ongoing Wheezing Illness Study in Leidsche Rijn (WHISTLER) prospective birth cohort study, which includes 3005 healthy newborns born between December 2001 and December 2012 in the Leidsche Rijn area of Utrecht, the Netherlands.
Introduction: For people with cystic fibrosis (CF), gaining access to elexacaftor/tezacaftor/ivacaftor (ETI) therapy, a new modulator drug combination, is perceived as a positive life event. ETI leads to a strong improvement of disease symptoms. However, some people with CF experience a deterioration in mental wellbeing after starting ETI therapy.
View Article and Find Full Text PDFUnlabelled: More than 25% of all children grow up with a chronic disease. They are at higher risk for developmental and psychosocial problems. However, children who function resiliently manage to adapt positively to these challenges.
View Article and Find Full Text PDFBackground: Children's views of health were explored in order to develop a health dialogue tool for children.
Methods: A qualitative research design was used as part of a codesign process. Based on semi-structured interviews with both healthy children and children with a chronic condition (aged 8-18).
Purpose: Adolescents might be susceptible to the effects of the COVID-19 lockdown. We assessed changes in mental wellbeing throughout the first year of the pandemic and compared these with prepandemic levels.
Methods: This five-wave prospective study among Dutch adolescents aged 12-17 years used data collected before the pandemic (n = 224) (T0), in May (T1), July (T2), and October 2020 (T3), and in February 2021 (T4).
The aim of this study was to assess the impact of the COVID-19 pandemic on the mental wellbeing of children 8-18 years old with chronic conditions, by comparing pandemic data with pre-pandemic data and with healthy peers. Data were obtained from two ongoing longitudinal cohorts: the PROactive cohort study following children with a chronic condition, and the WHISTLER population cohort. Mental wellbeing was assessed by three indicators: life satisfaction, internalising symptoms, and psychosomatic health.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to evaluate changes in mental well-being among Dutch adolescents during lockdown measures introduced due to COVID-19 and to assess differences between boys and girls in these changes.
- Results showed a significant decrease in life satisfaction for both genders after lockdown, with boys reporting worse scores than girls, while there were no changes in internalizing symptoms and an increase in psychosomatic health.
- Concerns related to COVID-19 were linked to lower life satisfaction and more internalizing symptoms, indicating a need for ongoing monitoring of mental well-being during the pandemic.
Objectives: To assess whether adolescents with asthma experience a lower mental well-being and lower general health than their peers without asthma.
Study Design: Data from the Prevention and Incidence of Asthma and Mite Allergy study were used. At the ages of 11, 14, 17, and 20 years, 2651, 2522, 2094, and 2206 participants, respectively, completed questionnaires.