Publications by authors named "Sabine Ammann"

The diagnosis of cardiac sarcoidosis, particularly in its isolated cardiac form, represents a major challenge due to non-specific symptoms and the limited sensitivity and specificity of basic cardiac investigations. MRI and metabolic PET-CT are important elements in the diagnostic process. Corticosteroids remain the cornerstone for the treatment of the inflammatory phase, in association with biological agents and steroid-sparing therapies.

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A pregnant woman presented with an asthma attack with a poor clinical evolution, requiring intubation. Medications traditionally used for the treatment of asthma in non-pregnant patients (short-acting beta-2 agonists, short-acting muscarinic antagonists, systemic corticosteroids) are considered safe during pregnancy, except for epinephrine. A systematic obstetrical evaluation is a key component in the evaluation and management of an asthmatic crisis during pregnancy.

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According to PubMed statistics when writing this review, the year 2022 is expected to mark the first dip in the number of articles published in relation to the Covid-19 pandemic. This review, without any mention to Sars-CoV-2, highlight this transition and addresses many topics in internal medicine: gastroenterology, cardiology, endocrinology, respiratory medicine, infectious diseases and venous access. Each year, the chief residents of the internal medicine ward in Lausanne university hospital (CHUV) in Switzerland meet up to share their readings: here is a selection of ten articles that have caught our attention, summarized and commented for you, which should change our daily practice.

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Article Synopsis
  • A 62-year-old woman experienced gradual neurological issues, presenting a diagnostic challenge for healthcare providers due to the non-specific nature of her symptoms.
  • The case underscores the need for a comprehensive diagnostic strategy that takes into account various potential conditions.
  • Emphasizing the importance of collaboration among different medical disciplines, the case shows how clinical, biological, and radiological data inform effective patient care.
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Disordered eating (DE) is known to predominate among girls, and historically studies have focused primarily on them. This cross-sectional study aimed to investigate the characteristics of adolescent and young adult males at risk of DE. Participants (N = 2269; 15-24 years) in a study assessing their lifestyle were divided into two groups based on the SCOFF five-question screening tool: a SCOFF[+] group for participants at risk of disordered eating, and a SCOFF[-] group for everyone else.

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Article Synopsis
  • The study examined how nine cell wall-degrading enzymes influenced the antimicrobial and antioxidant properties of bilberry against two human pathogens: Salmonella enterica and Staphylococcus aureus.
  • Treatment with these enzymes released phenolic compounds from the berry's cell wall, significantly boosting the antimicrobial activity, especially against Salmonella, when measured under acidic conditions.
  • Enzymatic treatments not only enhanced antimicrobial effects but also increased antioxidant activity by about 30%, with specific enzymes leading to varying increases in phenolic compounds and anthocyanins, demonstrating the potential for improved juice yield and health benefits.
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