Publications by authors named "Sabine Aimee Touangnou-Chamda"
Article Synopsis
- The epidemiology and ecology of Mycobacterium ulcerans (MU) infections are not well understood, especially regarding disease burden, host range, and transmission methods.
- A review of 155 articles from various countries showed MU's presence in humans, animals, plants, and environmental samples, with prevalence rates varying widely.
- Significant gaps exist in understanding the viability of MU in non-human reservoirs, prompting a need for further research on its transmission routes and host interactions.
Seroprevalence of hepatitis C virus antigen in patients with chronic liver disease and hepatocellular carcinoma at 12 week of treatment: a cross-sectional study.
Pan Afr Med J
January 2023
Introduction: epidemiological data suggests that more than 50% of hepatitis C virus (HCV) patients fail treatment. The objective of the study was to highlight the seroprevalence of hepatitis C virus antigen (HCV Ag) at the 12 week of treatment.
Methods: during a cross-sectional study, participants with chronic liver disease and hepatocellular carcinoma (HCC) were recruited between December 2020 and March 2022 at the Yaoundé General Hospital (HGY) and the University Teaching Hospital of Yaounde (UTHY).
This study aimed to assess the global prevalence of occult hepatitis B in blood donors. We searched PubMed, Web of Science, Global Index Medicus, and Excerpta Medica Database. Study selection and data extraction were performed by at least two independent investigators.
View Article and Find Full Text PDFBackground: Occult hepatitis C infection (OCI) is characterized by the presence of hepatitis C virus (HCV) RNA in the liver, peripheral blood mononuclear cells (PBMC) and/or ultracentrifuged serum in the absence of detectable HCV-RNA in serum. OCI has been described in several categories of populations including hemodialysis patients, patients with a sustained virological response, immunocompromised individuals, patients with abnormal hepatic function, and apparently healthy subjects.
Aim: To highlight the global prevalence of OCI.
Hepatitis B, C and D virus infections and risk of hepatocellular carcinoma in Africa: A meta-analysis including sensitivity analyses for studies comparable for confounders.
PLoS One
February 2022
Introduction: Africa denotes unique facies for hepatocellular carcinoma (HCC) characterized by a conjunction of low sensitization, restricted access to diagnosis and treatment and associated with the highest incidence and mortality in the world. We investigated whether hepatitis B (HBV), C (HCV) and D (VHD) viruses were etiological agents of HCC in Africa.
Methods: Relevant articles were searched in PubMed, Web of Science, African Index Medicus, and African Journal Online databases, as well as manual searches in relevant reviews and included articles.
Diabetes mellitus and tuberculosis, a systematic review and meta-analysis with sensitivity analysis for studies comparable for confounders.
PLoS One
February 2022
Article Synopsis
- The systematic review aimed to assess the relationship between diabetes mellitus (DM) and the risk of developing tuberculosis (TB), addressing confounders like age, gender, and lifestyle factors that previous studies may have overlooked.
- A total of 12,796 articles were screened, leading to the inclusion of 47 observational studies with over half a million DM or TB cases, and results indicated a significant association with an odds ratio of 2.3, meaning diabetics were more than twice as likely to develop TB compared to non-diabetics.
- The study confirmed that the increased TB risk persisted across various study types (cohort, case-control, cross-sectional) and was influenced by geographic differences, though the statistical significance remained consistent
Article Synopsis
- Hepatitis B virus (HBV) is a major global health issue, impacting around 2 billion people and causing about 1 million deaths annually, with healthcare workers (HCWs) at high risk due to potential exposure to infected blood.
- This study aims to assess the global prevalence of HBV serological markers among HCWs by analyzing relevant research published between 1970 and 2019, including a total of 227 studies from 71 countries.
- The meta-analysis revealed a pooled prevalence of current HBV infection (2.3%), with very low rates for HBeAg (0.2%) among the HCW population, highlighting the importance of monitoring and improving HBV control strategies in healthcare settings.