MULTIPLICATION AND SPREAD OF THE VIRUS OF ST. LOUIS ENCEPHALITIS IN MICE WITH SPECIAL EMPHASIS ON ITS FATE IN THE ALIMENTARY TRACT.

1. Beginning at 24 hours after intravenous injection of about 10 million intracerebral LD(50) of virus there was evidence of simultaneous, progressive multiplication in the brain and intestinal tract. 2.

PRODUCTION OF IMMUNITY TO DENGUE WITH VIRUS MODIFIED BY PROPAGATION IN MICE.

It has been demonstrated that dengue virus can be propagated by intracerebral inoculation in mice. Although initial adaptation to the mouse is a tedious and difficult process, 16 consecutive passages have been achieved already in one series and further passages are in progress. The virus propagated in mice produced dengue in human volunters, but was not pathogenic for cotton rats, hamsters, guinea pigs or rabbits.

THE NATURAL HISTORY OF EXPERIMENTAL POLIOMYELITIS INFECTION : I. STUDIES ON THE CENTRIFUGAL SPREAD AND ELIMINATION OF VIRUS IN INTRASCIATICALLY INOCULATED RHESUS MONKEYS.

1. Eight rhesus monkeys with experimental poliomyelitis following intrasciatic inoculation of "M.V.