Publications by authors named "Sabiha Mirza Khan"
ScientificWorldJournal
October 2006
Article Synopsis
- - Beta-thalassemia is a genetic disorder that leads to reduced red blood cell lifespan and severe anemia due to an imbalance in hemoglobin chains, primarily affecting the adult beta-globin chain.
- - Current treatments include regular blood transfusions and chelation therapy to manage iron overload, with newer strategies exploring fetal hemoglobin switching to improve red blood cell survival.
- - In a study involving 21 beta-thalassemia patients, autologous retrodifferentiated stem cell infusions significantly reduced transfusion needs, increased fetal hemoglobin production, and improved various blood parameters over a six-month period.
