Involvement of γ-Aminobutyric Acid and N-methyl-D-aspartate Receptors in Diabetic Gastropathy in Rats: Possible Beneficial Effect of Prolonged Treatment with Insulin and Magnesium Supplement.

Gastrointestinal dysfunction is a severe and common complication in diabetic patients. Some evidence shows that gamma-aminobutyric acid (GABA) and glutamate contribute to diabetic gastrointestinal abnormalities. Therefore, we examined the impact of prolonged treatment with insulin and magnesium supplements on the expression pattern of GABA type A (GABA-A), GABA-B, and N-methyl-D-aspartate (NMDA) glutamate receptors as well as nitric oxide synthase 1 (NOS-1) in the stomach of type 2 diabetic rats.

Neutrophil-to-lymphocyte ratio as an index of treatment response to trans-arterial chemoembolization in hepatocellular carcinoma.

Aim: We evaluated the response to Trans-arterial chemoembolization (TACE) in hepatocellular carcinoma (HCC) patients according to modified Response Evaluation Criteria in Solid Tumors (mRECIST) criteria. We determined the prognostic value of the neutrophil-to-lymphocyte ratio (NLR).

Background: TACE is the most commonly used method to treat patients with large, unresectable tumors or as bridge therapy in patients with HCC before liver transplantation.

Filamentation of a relativistic proton bunch in plasma.

We show in experiments that a long, underdense, relativistic proton bunch propagating in plasma undergoes the oblique instability, which we observe as filamentation. We determine a threshold value for the ratio between the bunch transverse size and plasma skin depth for the instability to occur. At the threshold, the outcome of the experiment alternates between filamentation and self-modulation instability (evidenced by longitudinal modulation into microbunches).

Hosing of a Long Relativistic Particle Bunch in Plasma.

Experimental results show that hosing of a long particle bunch in plasma can be induced by wakefields driven by a short, misaligned preceding bunch. Hosing develops in the plane of misalignment, self-modulation in the perpendicular plane, at frequencies close to the plasma electron frequency, and are reproducible. Development of hosing depends on misalignment direction, its growth on misalignment extent and on proton bunch charge.

Positive and negative cell therapy in randomized control trials for central nervous system diseases.

Neurorestorative cell therapies have been tested to treat patients with nervous system diseases for over 20 years. Now it is still hard to answer which kinds of cells can really play a role on improving these patients' quality of life. Non-randomized clinical trials or studies could not provide strong evidences in answering this critical question.

Advances in Neurorestoratology-Current status and future developments.

Neurorestoratology constitutes a novel discipline aimed at the restoration of damaged neural structures and impaired neurological functions. This area of knowledge integrates and compiles all concepts and strategies dealing with the neurorestoration. Although currently, this discipline has already been well recognized by physicians and scientists throughout the world, this article aimed at broadening its knowledge to the academic circle and the public society.

Collapsed Cone Superposition Algorithm Validation for Chest Wall Tangential Fields using Virtual Wedge Filters.

Background: Virtual wedge (VW) is used in radiotherapy to compensate for missing tissues and create a uniform dose distribution in tissues. According to TECDOC-1583 and technical reports series no. 430, evaluating the dose calculation accuracy is essential for the quality assurance of treatment planning systems (TPSs).

Health risk assessment of exposure to various vapors and fumes in a factory of automobile manufacturing.

This study aimed to comprehensively evaluate the health risk of exposure to various vapors and fumes in a factory of automobile manufacturing. This study was performed in 2021 on 115 workers. Vapors and fumes were gathered by the adsorbent tubes of activated charcoal and mixed cellulose esters (MCE) membrane filter, respectively.

Development and validation of a biological risk assessment tool among hospital personnel under COVID-19 pandemic conditions.

The need for a biological disease risk assessment method to prevent the contagion of these diseases, particularly among healthcare personnel, is crucial. Therefore, this study aimed to develop and validate a biological risk assessment tool for biological agents among hospital personnel under COVID-19 conditions. This cross-sectional study was performed on 301 employees in two hospitals.

Driving Fine and its Relationship with Dangerous Driving Behaviour Among Heavy Vehicle Drivers.

Context: There is a significant difference between actual and existing statistics of traffic fines; since some invisible fines and most of the visible traffic violations cannot be recorded by traffic officers. Therefore, dealing with driving fines and road fatalities is considered an important issue in social and public management worldwide.

Aims: Explore the factors associated with unsafe behaviors and getting traffic fines among a sample of Iranian heavy-vehicle professional drivers.

Distinct gene expression patterns of and variants in different types of brain tumours.

Numerous investigations have been recently published on the dysregulated expression of long-noncoding RNAs (lncRNAs) in various cancer types, emphasizing that abnormal lncRNA expression is a major contributor to tumourigenesis. A broad spectrum of lncRNAs is expressed in the central nervous system, where these RNAs seem to play key roles in brain development and function. In addition to expressing , a master regulator of pluripotency that lies within its third intron, lncRNA has a proposed role in regulating neural development.

Biomechanical changes of the common carotid artery and internal jugular vein in patients with multiple sclerosis.

Purpose: Investigations of the hemodynamic changes of the venous system in patients with multiple sclerosis (MS) have shown contradictory results. Herein, the biomechanical parameters of the internal jugular vein (IJV) and common carotid artery (CCA) of MS patients were extracted and compared to healthy individuals.

Methods: B-mode and Doppler sequential ultrasound images of 64 IJVs and CCAs of women including 22 healthy individuals, 22 relapsing-remitting multiple sclerosis (RRMS) patients, and 20 primary-progressive multiple sclerosis (PPMS) patients were recorded and processed.

Respiratory functions and health risk assessment in inhalational exposure to vinyl acetate in the process of carpet manufacturing using Monte Carlo simulations.

Vinyl acetate (VA) is a volatile compound and the main compound of the carpenter's glue. VA causes upper respiratory tract irritation, cough, and hoarseness in occupational exposure. As Iran is one of the biggest carpet producers in the world, this study was carried out to determine the inhalational health risk for employees exposed to VA.

Validity and reliability of the Persian version of the WH-Question comprehension test in children With autism.

Questions form essential components of everyday speech; therefore, it is appropriate to evaluate children with autism to understand what they are asking during the daily conversation. A proper tool is required to assess questions formed through interrogative pronouns (what are commonly known as Wh-questions). The present study investigates the validity and reliability of the WH-Question comprehension test in children with autism.

Analysis of the research subjects and hot topics of occupational diseases through the Web of Science from 1975 to 2021.

A variety of studies have been conducted in Occupational diseases (ODs) and this makes it difficult for researchers to identify new areas of study. Therefore, the present study was conducted by examining Web of Science data to identify hot topics and research topics on ODs. This is a scientometric study performed using CiteSpace and Gephi software for statistical analysis.

Measurement of barriers to perform periodic examinations: development and psychometric properties scale.

Due to recent changes in workplace risks, it is required to investigate the motivations of employees and employers for occupational examination performance. This study aims to develop a self-report scale to overcome prior methodological defects and evaluate barriers of performing periodic examinations. The study was conducted with 200 participants, including employers, occupational health inspectors, occupational physicians and occupational health experts working in the industrial sector, aged 25-70 years.

Comparison of pregnancy outcome during pandemic of COVID-19 and non-pandemic situations, Yazd, Iran, in 2019-2020.

This study aimed to compare the pregnancy outcomes during pandemic and non-pandemic COVID-19 in women referred to health service centres in Yazd. This descriptive study was performed based on the information obtained from all pregnant women referred to comprehensive health service centres in Yazd city using census method, between March 21 2019 and December 21 2019 and between March 20 2020 and December 20 2020. The pregnant mothers' information, including their pregnancy outcome, and maternal and neonatal complications, was extracted from the electronic health information system of Yazd city.

Comparing Geant4 physics models for proton-induced dose deposition and radiolysis enhancement from a gold nanoparticle.

Gold nanoparticles (GNPs) are materials that make the tumor cells more radiosensitive when irradiated with ionizing radiation. The present study aimed to evaluate the impact of different physical interaction models on the dose calculations and radiochemical results around the GNP. By applying the Geant4 Monte Carlo (MC) toolkit, a single 50-nm GNP was simulated, which was immersed in a water phantom and irradiated with 5, 50, and 150 MeV proton beams.

Artificial Neural Network to Forecast Enhanced Oil Recovery Using Hydrolyzed Polyacrylamide in Sandstone and Carbonate Reservoirs.

Polymer flooding is an important enhanced oil recovery (EOR) method with high performance which is acceptable and applicable on a field scale but should first be evaluated through lab-scale experiments or simulation tools. Artificial intelligence techniques are strong simulation tools which can be used to evaluate the performance of polymer flooding operation. In this study, the main parameters of polymer flooding were selected as input parameters of models and collected from the literature, including: polymer concentration, salt concentration, rock type, initial oil saturation, porosity, permeability, pore volume flooding, temperature, API gravity, molecular weight of the polymer, and salinity.

Assessing the short-term effects of radiotherapy on the shear modulus of the common carotid artery as a new biomarker of radiation-induced atherosclerosis.

Purpose: The purpose of this study was to investigate the incidence of short-term atherosclerosis in the common carotid arteries following radiotherapy.

Methods: The mean radiation dose to the arteries was 49.30±15.

Evaluation of Hippocampal Function in Temporal Lobe Epilepsy: Spatial Bayesian Variable Selection and Grouping the Regression Coefficient in Multilevel Functional Magnetic Resonance Imaging Data Analysis.

Background: A pre-surgical evaluation of cognitive functions in patients with mesial temporal lobe epilepsy (mTLE) is critical. The limitations of the usual brain analysis model were resolved by the spatial Bayesian variable selection (SBVS) method. An Ising and Dirichlet Process (Ising-DP) model considers SBVS and the grouping of a large number of voxels.

Prevalence of Posttraumatic Stress Disorder Following the Earthquake in Iran and Pakistan: A Systematic Review and Meta-Analysis.

Posttraumatic stress disorder (PTSD) is a common mental disorder following traumatic events. The present study was conducted to understand the prevalence of PTSD after the earthquake in Iran and Pakistan. The review includes all articles published from inception to March 2019.