Serum zinc and copper status in Iranian patients with pemphigus vulgaris.

Background: The role of nutritional factors including trace elements has been reported in the pathogenesis of many autoimmune diseases.

Objective: Regarding the relatively high prevalence of pemphigus vulgaris in Iran, we investigated the serum levels of zinc and copper as two important trace elements, together with the oxidative stress status in patients with pemphigus vulgaris.

Materials And Methods: This case-control study was performed on 25 patients with newly diagnosed pemphigus vulgaris and 25 age- and sex-matched healthy control subjects.