Clinical Manifestations.

Background: The role of neuropsychiatric symptoms (NPS) as early markers of cognitive impairment progression along the cognitive impairment continuum needs further research. Our objective was to estimate to which extent NPS, measured with the Mild Behavioral Impairment Checklist (MBI-C), predict time-to-cognitive-worsening during follow-up in a sample of older adults recruited from primary care centers while controlling for other related variables (i.e.

Clinical Manifestations.

Background: Language performance has been considered a potential screening tool in the continuum from healthy cognitive aging to cognitive impairment and dementia. Language impairment and most notably impairment in semantic verbal fluency has been shown to increase with the progress in this continuum (Liampas et al., 2023).

Clinical Manifestations.

Background: Higher recency effect in episodic memory (EM) has been found for MCI and dementia (Martin et al., 2013; Campos et al., 2016).

Relevance of Complaint Severity in Predicting the Progression of Subjective Cognitive Decline and Mild Cognitive Impairment: A Machine Learning Approach.

Background: The presence of subjective cognitive complaints (SCCs) is a core criterion for diagnosis of subjective cognitive decline (SCD); however, no standard procedure for distinguishing normative and non-normative SCCs has yet been established.

Objective: To determine whether differentiation of participants with SCD according to SCC severity improves the validity of the prediction of progression in SCD and MCI and to explore validity metrics for two extreme thresholds of the distribution in scores in a questionnaire on SCCs.

Methods: Two hundred and fifty-three older adults with SCCs participating in the Compostela Aging Study (CompAS) were classified as MCI or SCD at baseline.