Publications by authors named "Sabbir Raihan"
Liver fibrosis, developed in almost all chronic liver injuries. Epidermal growth factor receptors (EGFR) have been thought to contribute to cirrhosis and liver fibrosis. Therefore, using a rat model of carbon tetrachloride (CCl)-induced liver fibrogenesis, we investigated the preventive effects of cetuximab, an inhibitor of the EGF receptor (EGFR).
View Article and Find Full Text PDFMinerals are critical for maintaining overall health. These tiny chemical compounds are responsible for enzymatic activation, maintaining healthy teeth and bones, regulating energy metabolism, enhancing immunity, and aiding muscle and brain function. However, mineral deficiency in the form of inadequate or under nourished intake affects millions of people throughout the world, with well-documented adverse health consequences of malnutrition.
View Article and Find Full Text PDFAnti-inflammatory Property of AMP-activated Protein Kinase.
Antiinflamm Antiallergy Agents Med Chem
November 2020
Article Synopsis
- The research explores the complex relationship between inflammation and immune response, questioning whether increased inflammation leads to enhanced healing or greater risk for autoimmune diseases.
- A comprehensive review of studies conducted since 2010 was performed to investigate the role of inflammation, AMPK, and their impact on treating various disorders, suggesting that AMPK may help mitigate inflammation-related issues.
- The conclusion emphasizes the intricate nature of inflammation's role in immunity, proposing that AMPK could be a valuable target for therapies aimed at controlling diabetes, obesity, and autoimmune diseases, despite ongoing debates in the field.
Through a simple PEG-conjugation of the natural product Amorfrutin B, we enhanced its pharmacokinetic profile. The PEGylated molecule displayed significantly improved gastrointestinal absorption (p<0.05) and had a longer systemic circulation life (p<0.
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