Publications by authors named "Sabah Shaikh"
Article Synopsis
- - The study examined gene copy number variation (CNV) in a large group of 7,100 children and youth, focusing on its impact on mental health, cognitive functioning, and physical health.
- - Clinically relevant CNVs were found in 3.9% of participants and were linked to higher ADHD traits, cognitive deficits, and increased occurrence of specific mental health diagnoses like ADHD, autism spectrum disorder, and learning disorders.
- - The research highlights the role of rare genetic deletions in brain-related gene sets, suggesting they contribute to ADHD characteristics, and sets a baseline for understanding genetic factors in mental health issues among youth during a growing crisis.
Low blood levels of long chain omega-3 polyunsaturated fatty acids (LC n-3 PUFA) have been reported to be associated with increased risk for cardiovascular disease (CVD) deaths. Systematic studies measuring LC n-3 PUFA blood levels (pre and post-treatment) in defined subjects, and monitoring the correction of nutritional deficiency with a pure LC n-3 PUFA formulation in sufficient doses, while monitoring CVD risk factors are lacking. We tested the efficacy of a novel LC n-3 PUFA Medical Food formulation (VASCAZEN(®), > 90 % pure with a 6:1 eicosapentaenoic acid-(EPA):docosahexaenoic acid-(DHA) ratio; 6:1-OM3), to correct such deficiency and determine the concomitant effects on lipid profiles.
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