Thorough examination of the potential biological implications of the cuproptosis-related gene LIPT2 in the prognosis and immunotherapy in pan-cancer.

Objectives: To elucidate the expression levels and prognostic value of the Lipoyltransferase 2 (LIPT2) gene in a pan-cancer view.

Methodology: Our study comprehensively investigated the role of LIPT2 in pan-cancer, combining bioinformatics analyses with experimental validations.

Results: Analysis of LIPT2 mRNA expression across various cancers revealed a significant up-regulation in 18 tumor types and down-regulation in 8 types, indicating its diverse involvement.

Does frequent hemodialysis regimen results in regression of left ventricular mass compared to conventional hemodialysis?

Several advances in dialysis therapies have been made. Still, the mortality in end-stage renal disease (ESRD) remains high at rates exceeding 15%. Cardiovascular disease from heart failure or sudden death remains an important cause for mortality in these groups.

Overview of management of acute renal failure and its evaluation; a case analysis.

The annual incidence is about 150 per million in the UK, but this figure is six times greater in the >80 years old group. Prerenal azotemia is considered as the most serious reason in community or hospital acquired acute renal failure (ARF). A 67-year-old middle age male was admitted to the hospital with a chief complaint of generalized weakness, volume depletion and dysuria.

Accomplishing dietary and biochemical standards and improving hemodialysis efficiency with a non-compliant patient; a case study.

Background: It was not until mid nineties when UK (RAS) and US (K/DOQI) first launched the nutritional and biochemical standards for haemodialysis in patients with ESRF. The present case is related to a patient who's blood results diverged widely from the nutritional and biochemical standards set by the RAS. And how the multidisciplinary team with this patient aimed to achieve these standards.