The Effect of Probiotic Plus Prebiotic Supplementation on the Tolerance and Efficacy of Eradication Quadruple Therapy: a Randomized Prospective Double Blind Controlled Trial.

BACKGROUND Standard anti-H () treatment fails in the eradication of the organism in almost 10-35% of the patients and has different side effects. Recent studies have proposed that probiotic supplementations with or without prebiotic may improve the eradication rate and diminish the side effects, although it is still a controversial issue. We aimed to investigate the effect of probiotic with prebiotic supplementation on the eradication rate and side effects of anti quadruple therapy.