MCC950 in the treatment of NLRP3-mediated inflammatory diseases: Latest evidence and therapeutic outcomes.

Evidence suggests that various innate immune system components are involved in pathological inflammatory conditions. Among these components, the NLR family pyrin domain containing 3 (NLRP3) as an inflammasome can participate in destructive inflammatory responses by inducing the production of the active form of inflammatory cytokines. The NLRP3 could be involved in the pathogenesis of several inflammatory and autoimmune diseases such as type 2 diabetes mellitus, multiple sclerosis (MS), atherosclerosis, Alzheimer's disease (AD), cryopyrin-associated periodic syndrome (CAPS), and infectious diseases.

Development of a body joint angle measurement system using IMU sensors.

This paper presents an approach for measuring and monitoring human body joint angles using inertial measurement unit (IMU) sensors. This type of monitoring is beneficial for therapists and physicians because it facilitates remote assessment of patient activities. In our approach, two IMUs are mounted on the upper leg and the lower leg to measure the Euler angles of each segment.