Publications by authors named "Saarang Patel"

Article Synopsis
  • Pituitary apoplexy is a serious condition often linked to underlying masses like adenomas, causing acute neurological symptoms that may require urgent surgical intervention.
  • The study compares the effects of different surgical timing (before or after 48 hours, 72 hours, and 7 days) on visual outcomes for patients with this condition, along with the effectiveness of surgical decompression versus conservative management.
  • A review of 29 studies found that most patients had visual deficits and were treated with surgery, particularly through the endoscopic endonasal approach, with a detailed analysis focusing on outcomes over a 7-day period.
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  • - Extended reality (XR), which includes augmented reality (AR), virtual reality (VR), and mixed reality (MR), has significant potential in endovascular neurosurgery, particularly for improving training and understanding of complex cerebrovascular imaging.
  • - A systematic review identified 19 studies, revealing that VR was the most utilized modality for educational purposes, primarily for simulation and anatomical modeling, while AR was used for live guidance and MR for modeling and teaching during operations.
  • - The use of VR and MR in anatomical education provides detailed, patient-specific 3-D models, enhancing the learning experience; however, there are challenges like inaccurate tracking of surgical tools that need to be addressed for effective implementation in training.
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  • Social media helps patients with rare diseases, like arteriovenous malformations (AVM), connect and share experiences, as shown in an analysis of posts from platforms like Twitter, Instagram, and TikTok.
  • The study found that common themes in posts included raising awareness (87%), recounting symptoms (50.2%), and sharing positivity (17.5%), with most engagement coming from female users.
  • Social media serves as a crucial platform for AVM patients to connect with others and discuss their experiences, increasing public awareness about the condition.
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Background And Objectives: Flow diversion (FD) of intracranial aneurysms (IAs) is an increasingly used and efficacious treatment modality. Transcirculation approaches, or approaches that cross the contralateral or anteroposterior arterial supply before reaching a target vessel, have been used to treat cerebrovascular pathologies when traditional approaches are unsuitable or require intraoperative complication management. This study sought to review IAs treated with FD using a transcirculation approach to determine the technique's safety and efficacy.

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Objective: Axel Perneczky is responsible for conceptualizing the "keyhole" philosophy as a new paradigm of minimal invasiveness within cranial neurosurgery. Keyhole neurosurgery aims to limit approach-related traumatization and minimize brain retraction while still enabling the neurosurgeon to achieve operative goals. The supraorbital keyhole craniotomy (SOKC) and minipterional (pterional keyhole, PKC) approaches have become mainstays for clipping intracranial aneurysms.

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Anterior column realignment via anterior, oblique, or lateral lumbar interbody fusion is increasingly recognized as a powerful mechanism for indirect decompression and sagittal realignment in flexible deformity. Single-position lateral surgery is a popular variation that places patients in the lateral decubitus position, allowing concomitant placement of lateral interbodies and posterior segmental instrumentation without the need for repositioning the patient. The addition of robotics to this technique can help to overcome ergonomic limitations of the placement of pedicle screws in the lateral decubitus position; however, its description in the literature is relatively lacking.

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Article Synopsis
  • * The WEB has significantly more citations (mean 35.6) compared to other intrasaccular flow disruptors (mean 4.24), with most studies being retrospective reviews and a noticeable lack of contributions from African authors.
  • * The analysis highlights that leading countries in WEB research (like France) differ from those contributing to other flow disruptors (like Germany), indicating a skew in global research collaboration and production, primarily concentrated in Europe and North America.
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We report a rare case of acute ischemic stroke from concurrent large vessel occlusions (LVOs) and subsequent successful mechanical thrombectomy revascularization in a patient with active coronavirus disease 2019 (COVID-19) pneumonia. A 59-year-old woman presented to the emergency department after one week of intermittent chest pain, dyspnea, and diarrhea found to have COVID-19 pneumonia. On hospital day three, the patient developed acute altered mental status and hemiparesis with a National Institutes of Health Stroke Scale (NIHSS) of 22.

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Background: Recent advances in total knee arthroplasty (TKA) have been driven by a growing focus on evidence-based medicine. This transition is reflected in the critical appraisal of both, the quality of work and the potential impact on the orthopedic community. The purpose of our study was to (1) identify the top 100 most-cited articles in TKA in the last decade and from all-time, and (2) compare methodological rigor of the most-cited articles in TKA in the last decade to articles all-time by level of evidence.

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Background: The social determinants of health, which influence healthcare access, patient outcomes, and population-level burden of disease, contribute to health disparities experienced by marginalized patient populations. In the present study, we sought to evaluate the landscape of health disparities research within neurosurgery.

Methods: Embase, Ovid-MEDLINE, Scopus, Web of Science, Cochrane Library, and ProQuest Dissertations databases were queried for original research on health disparities regarding access to, outcomes of, and/or postoperative management after neurosurgical procedures in the United States.

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/Summary. A 39-year-old female with a notable medical history of smoking and a familial predisposition to unruptured aneurysms presented with clinical symptoms of intermittent right-sided headaches, flashes of light, and pulsatile tinnitus in the right ear. Diagnostic evaluations, including advanced angiographic techniques, identified a right occipital arteriovenous malformation (AVM).

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Introduction: Arthrofibrosis occurs in up to 10% of patients who undergo total knee arthroplasty (TKA). For cases that are not amenable to manipulation under anesthesia (MUA), there is little consensus on how many components should be revised. We compared outcomes of polyethylene exchanges, when doing lysis of adhesions (LOA) versus full component revision.

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Article Synopsis
  • Staged surgery is often used for skull base lesions to improve outcomes and minimize risks, but its application for primary intraparenchymal tumors is less common and under-researched.
  • A systematic review analyzed 7 studies focusing on the unique indications, timing, surgical methods, and complications associated with staged surgeries for these types of brain tumors.
  • Results indicated that pediatric patients more frequently underwent staged surgeries, with shorter intervals between operations compared to adults, and differing complications based on age groups, highlighting a need for targeted strategies in surgical approaches.
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Background Context: Frailty is a common comorbidity associated with worsening outcomes in various medical and surgical fields. The Hospital Frailty Risk Score (HFRS) is a recently developed tool which assesses frailty using 109 International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM) comorbidity codes to assess severity of frailty. However, there is a paucity of studies utilizing the HFRS with patients undergoing anterior cervical discectomy and fusion (ACDF) for cervical spondylotic myelopathy (CSM).

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Background: Social media is becoming increasingly prominent in neurosurgery. However, the specifics of using social media as a tool for patient education have not yet been synthesized. In this narrative review, we provide an overview of opportunities, challenges, and best practices in the use of social media for patient education in neurosurgery.

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Background: Affective disorders, such as depression and anxiety, are exceedingly common among patients with metastatic cancer. The aim of this study was to investigate the relationship between affective disorders and health care resource utilization in patients undergoing surgery for a spinal column metastasis.

Methods: A retrospective cohort study was performed using the 2016-2018 National Inpatient Sample database.

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Corpus callosotomy is among the oldest surgeries performed for drug-resistant epilepsy. Since it was first performed in 1940, numerous studies have assessed its outcomes in various patient populations in addition to describing different extents of sectioning and emerging technologies (i.e.

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Epilepsy is a chronic seizure disorder that affects about 1% of the global population.1 When seizure freedom cannot be obtained solely through antiseizure medicines (ASMs), the condition is termed medically refractory epilepsy (MRE).2,3 Though posterior quadrant disconnection (PQD) is underutilized in our experience, it is a highly effective surgical procedure for MRE restricted to the temporal, parietal, and/or occipital lobes.

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The objective of this report is to present a rare case of a recurrence after 20 years of retroperitoneal dedifferentiated liposarcoma after surgical resection and to discuss the lessons learned from this rare phenomenon for patients management and understanding the behavior of these aggressive tumors.  A 75-year-old woman presented with recurrent retroperitoneal dedifferentiated liposarcoma who had undergone a surgical resection 20 years earlier and had no evidence of disease on frequent follow-ups during that period. The histopathologic examination revealed different morphologic characteristics between the initial and recurrent presentations.

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