Publications by authors named "Saahil Jumkhawala"

Article Synopsis
  • The study aimed to evaluate the safety and effectiveness of protamine as a reversal agent for heparin during percutaneous coronary interventions (PCI).
  • Although protamine is not commonly used for this purpose due to concerns about stent thrombosis, the analysis involved 11 studies that assessed its impact on various outcomes, including stent thrombosis, mortality, and complications.
  • The results indicated that using protamine did not increase the risk of stent thrombosis or mortality, and it was associated with fewer major bleeding complications and shorter hospital stays.
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Background: Smoking is the leading preventable cause of death in the United States, but evidence-based smoking cessation therapy is underutilized. Financial incentive strategies represent an innovative approach for increasing the use of counseling and pharmacotherapy. If effective, they could supplement or supplant resource-intensive policy options, particularly in populations for whom smoking has substantial societal costs.

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Background: The American College of Cardiology/American Heart Association (ACC/AHA) recently published a rigorous framework to guide integration of economic data into clinical guidelines. We assessed the quality of economic evaluations in a major ACC/AHA clinical guidance report.

Methods: We systematically identified cost-effectiveness analyses (CEAs) of RCTs cited in the ACC/AHA 2012 Guideline for the Diagnosis and Management of Patients with Stable Ischemic Heart Disease.

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Background: Appropriate use criteria (AUC) for cardiac stress tests address concerns about utilization growth and patient safety. We systematically reviewed studies of appropriateness, including within physician specialties; evaluated trends over time and in response to AUC updates; and characterized leading indications for inappropriate/rarely appropriate testing.

Methods: We searched PubMed (2005-2015) for English-language articles reporting stress echocardiography or myocardial perfusion imaging (MPI) appropriateness.

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