Publications by authors named "Saadiq Garba"
PLoS Pathog
December 2023
Article Synopsis
- * gp120 also interacts with the integrin ⍺4β7, which is found on certain memory CD4+ T cells, suggesting that this relationship is important for HIV's preference for these immune cells and gut tissues.
- * The study reveals that CD4 binds to ⍺4β7 dynamically, with specific binding sites that are crucial for both gp120's attachment to CD4 and its entry into cells, indicating that the interaction between CD4 and ⍺4β7 is critical
Open Forum Infect Dis
November 2023
Article Synopsis
- California leads the U.S. in tuberculosis (TB) cases, prompting a study on missed chances for latent tuberculosis infection (LTBI) screening in patients diagnosed with active TB.
- The study examined Kaiser Permanente Southern California patients over 11 years, revealing that a significant majority—82%—of those with TB disease had not been pre-screened for LTBI, which could have led to earlier treatment.
- The findings indicate that only one-fifth of patients were screened for LTBI prior to their TB diagnosis, highlighting a critical need for improved screening practices to prevent future TB cases.
