Is sputum cytology reliable for detection of atypical lung epithelial proliferative changes triggered by cigarette smoking?

Background: In recent years, Saudi Arabia has witnessed major tobacco smoking-related disease, such as cardiovascular disease and cancer, particularly among the younger population.

Methodology: The present study aimed at evaluating the effect of cigarette smoke on lung epithelial cells.

Results: This was a cross-sectional case-control study involving 300 apparently healthy volunteers living in Ha'il, Northern Saudi Arabia.

Frequency and genotype of human papillomavirus among Sudanese patients with head and neck tumours.

Objectives: The aim of this study was to determine the frequency and genotype of human papillomavirus (HPV) infections in head and neck squamous cell carcinomas (HNSCCs) and benign head and neck tumours.

Methodology: A retrospective study was performed on 150 samples of patients diagnosed with HNSCCs and 50 samples obtained from patients diagnosed with benign head and neck tumours. Tumour DNA was amplified using polymerase chain reaction (PCR) with HPV consensus and multiplex primers.

Human papilloma virus attributable head and neck cancer in the sudan assessed by p16INK4A immunostaining.

Background: The aim of this study was to screen for human papillomavirus (HPV) infections in head and neck squamous cell carcinomas (HNSCCs) using P16 immunostaining.

Materials And Methods: A retrospective study was performed on 150 samples from patients diagnosed with HNSCCs. HPV status was determined using p16INK4A.