Publications by authors named "Saada Legesse"
Physiol Rep
November 2020
Article Synopsis
- Obesity and insulin resistance are common outcomes of a high-fat diet (HFD), so researchers studied the effects of succinic acid (SA) on metabolism in mice with HFD-induced obesity.
- Mice on both low-fat (LFD) and high-fat diets were tracked over several months, showing that while SA reduced fat mass in the HFD group, it did not significantly influence body weight, insulin, or glucose levels.
- Despite the lack of positive effects on glucose regulation, SA appeared to enhance mitochondrial respiration and potential muscle health by increasing the overall mitochondrial content.
