Boswellia serrata Powder Regimen Provides Significant Protection Against Renal Damage and Blood Imbalances in Diabetic Rats.

Diabetic kidney disease affects approximately one-third of diabetes patients. Hyperglycemia and oxidative stress contribute to this condition. Boswellia serrata gum resin is known for its antioxidant properties and potential in managing diabetic complications, though its nephroprotective effects are not well documented.

Phenolic Profiling, In Vitro Antiglycation, Antioxidant Activities, and Antidiabetic Effect of Algerian Trigonella Foenum-Graecum L. in Rats Administered a β-Cell Toxicant.

This study sought to quantitatively assess individual and total polyphenols, mineral composition, antioxidant and antiglycation activities of Algerian fenugreek seeds (AFS) as well as the antidiabetic effect of its supplementation on streptozotocin-induced diabetic rats. Forty rats were divided into four groups (i) non diabetic rats, (ii) non diabetic rats +10 % AFS, (iii) diabetic rats, (iv) diabetic rats +10 % AFS. Flame-SAA analysis revealed a rich content in micro-elements, HPLC DAD-FLD analysis revealed twenty components with rutin and ferulic acid being the major compounds in AFS hydro-methanolic extract while spectrophotometric assays scrutinized moderate contents in total phenolics and flavonoids.

The investigation of the efficacy ratio of cress seeds supplementation to moderate hyperglycemia and hepatotoxicity in streptozotocin-induced diabetic rats.

Objective: Oxidative stress resulting from chronic hyperglycemia induced many complications in diabetes and led to disorders and dysfunctions in different organs. This study aimed to evaluate the hepatoprotective rate of cress seeds (CS) or seeds in the diet on lowering hyperglycemia and oxidative stress damaging.

Methods: Diabetes was induced by a single intraperitoneal injection of 60 mg/kg of streptozotocin (STZ).

The investigation of the oxidative stress-related parameters in type 2 diabetes mellitus.

Objective: Oxidative stress, defined as an imbalance between reactive oxygen species production and breakdown by endogenous antioxidants, is closely associated with diabetes mellitus. The diabetes is characterized by hyperglycemia together with biochemical alterations of glucose and lipid peroxidation. Oxidative stress has been implicated in the pathogenesis of type 2 diabetes and its complications.

Protective effect of ginger against toxicity induced by chromate in rats.

The evaluation of the effect of ginger on the modulation of toxic effects induced by chromate is the objective of our study. 50 male rats Albinos Wistar were divided to five groups as follow: group I (T) is served as control, received a mineral water by gavage (per os); group II (G) received an experimental diet with 2% of ginger; group III (Cr) received an oral dose of potassium dichromate (15 mg/kg) and normal diet; group IV (CrG): received an oral dose of potassium dichromate (15 mg/kg) and an experimental diet containing 2% ginger; and group V (Cr(+)G) received an oral dose of potassium dichromate (25 mg/kg) and an experimental diet with 2% of ginger. The results of this study indicate that the chromate provoked a haematoxic effect (anemia), nephrotoxic, hepatotoxic, and also a perturbation in lipids profile.