Bioactive Self-Nanoemulsifying Drug Delivery Systems (Bio-SNEDDS) for Combined Oral Delivery of Curcumin and Piperine.

: Bioactive oils of natural origin have gained huge interests from health care professionals and patients. : To design a bioactive self-nanoemulsifying drug delivery system (Bio-SNEDDS) comprising curcumin (CUR) and piperine (PP) by incorporating bioactive natural oils in the formulation. : The self-emulsifying properties of apricot, avocado, black seed and seed oils were screened within various SNEDDS formulations.