The "Known Unknowns" of Kleine-Levin Syndrome: A Review and Future Prospects.

Kleine-Levin syndrome (KLS) is a rare, homogeneous, debilitating sleep disorder characterized by episodic hypersomnia, cognitive impairment, and behavioral changes. The etiology, pathophysiology, and optimal management of KLS remain uncertain. We identify the 5 key areas requiring urgent attention: KLS immunopathogenesis studies, next-generation genetics, multimodal functional imaging, biomarker discovery, and clinical drug trials.

Impact of students in non-teaching hospitals.

Background: The placement of medical students in non-teaching hospitals is the norm worldwide. The suggestion that teaching standards are inferior in non-teaching hospitals has been studied and refuted. This study explores this from a different perspective: the impact of medical student presence on the teachers, hospital environment and patient care at King Saud Medical City, as assessed by clinical supervisors.

Feasibility and Outcomes of Oncology Teaching for 5th Year Medical Students.

This study explored medical students' opinions of undergraduate oncology teaching, aiming to define optimal strategies for nonspecialist oncology teaching. A cross-sectional study was conducted at Al Imam Muhammed Ibn Saud Islamic University, Riyadh, Saudi Arabia. Between August 2014 and June 2015, 124 medical students completing the oncology course in the fifth year at the College of Medicine, Al Imam Muhammed Ibn Saud Islamic University, were given a 47-item questionnaire.

Kleine-Levin syndrome. Familial cases and comparison with sporadic cases.

Objectives: To highlight the occurrence of familial cases and addresses, whether familial Kleine-Levine syndrome (KLS) presents the same spectrum of disease, as that seen in sporadic KLS.  

Methods: Between September and December 2014, reports of familial cases of KLS were identified by searching the Library of Congress, PubMed, and Web of Science databases restricted to the English language, with no restriction on date of publication. All cases were reviewed to identify familial cases consistent with current diagnostic criteria for sporadic KLS.