In vivo intravascular photoacoustic imaging of plaque lipid in coronary atherosclerosis.

Prospective identification of lipid-rich vulnerable plaque has remained an elusive goal. Intravascular photoacoustics, a hybrid optical and ultrasonic technology, was developed as a tool for lipid-rich plaque imaging. Here, we present the first in vivo images of lipid-rich coronary atherosclerosis acquired with this new technology in a large animal model, and relate them to independent catheter-based imaging and histology.

Naturally Occurring Shear Waves in Healthy Volunteers and Hypertrophic Cardiomyopathy Patients.

We apply a high frame rate (over 500 Hz) tissue Doppler method to measure the propagation velocity of naturally occurring shear waves (SW) generated by aortic and mitral valves closure. The aim of this work is to demonstrate clinical relevance. We included 45 healthy volunteers and 43 patients with hypertrophic cardiomyopathy (HCM).

Search for W Boson Decays to Three Charged Pions.

For the first time, a search for the rare decay of the W boson to three charged pions has been performed. Proton-proton collision data recorded by the CMS experiment at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 77.3  fb^{-1}, have been analyzed.

Jet Shapes of Isolated Photon-Tagged Jets in Pb-Pb and pp Collisions at sqrt[s_{NN}]=5.02 TeV.

The modification of jet shapes in Pb-Pb collisions, relative to those in pp collisions, is studied for jets associated with an isolated photon. The data were collected with the CMS detector at the LHC at a nucleon-nucleon center-of-mass energy of 5.02 TeV.

Lack of meaning, purpose and direction in life in personality disorder: A comparative quantitative approach using Livesley's General Assessment of Personality Disorder.

Meaning in life is a motivational force and an existential theme for many people. The concept of meaning comprises purpose, comprehension and mattering. According to the Section III model of personality disorder (DSM-5), lack of meaning, purpose and direction in life is part of personality dysfunction.

Photoacoustic imaging for guidance of interventions in cardiovascular medicine.

Imaging guidance is paramount to procedural success in minimally invasive interventions. Catheter-based therapies are the standard of care in the treatment of many cardiac disorders, including coronary artery disease, structural heart disease and electrophysiological conditions. Many of these diseases are caused by, or effect, a change in vasculature or cardiac tissue composition, which can potentially be detected by photoacoustic imaging.

Measurement of the top quark mass in the all-jets final state at and combination with the lepton+jets channel.

A top quark mass measurement is performed using of LHC proton-proton collision data collected with the CMS detector at . The measurement uses the all-jets final state. A kinematic fit is performed to reconstruct the decay of the  system and suppress the multijet background.

Search for Dark Matter Particles Produced in Association with a Top Quark Pair at sqrt[s]=13 TeV.

A search is performed for dark matter particles produced in association with a top quark pair in proton-proton collisions at sqrt[s]=13  TeV. The data correspond to an integrated luminosity of 35.9  fb^{-1} recorded by the CMS detector at the LHC.

Observation of Two Excited B_{c}^{+} States and Measurement of the B_{c}^{+}(2S) Mass in pp Collisions at sqrt[s]=13 TeV.

Signals consistent with the B_{c}^{+}(2S) and B_{c}^{*+}(2S) states are observed in proton-proton collisions at sqrt[s]=13  TeV, in an event sample corresponding to an integrated luminosity of 143  fb^{-1}, collected by the CMS experiment during the 2015-2018 LHC running periods. These excited b[over ¯]c states are observed in the B_{c}^{+}π^{+}π^{-} invariant mass spectrum, with the ground state B_{c}^{+} reconstructed through its decay to J/ψπ^{+}. The two states are reconstructed as two well-resolved peaks, separated in mass by 29.

Observation of Single Top Quark Production in Association with a Z Boson in Proton-Proton Collisions at sqrt[s]=13 TeV.

The observation of single top quark production in association with a Z boson and a quark (tZq) is reported. Events from proton-proton collisions at a center-of-mass energy of 13 TeV containing three charged leptons (either electrons or muons) and at least two jets are analyzed. The data were collected with the CMS detector in 2016 and 2017 and correspond to an integrated luminosity of 77.

Search for resonant production of second-generation sleptons with same-sign dimuon events in proton-proton collisions at .

A search is presented for resonant production of second-generation sleptons ( , ) via the -parity-violating coupling to quarks, in events with two same-sign muons and at least two jets in the final state. The smuon (muon sneutrino) is expected to decay into a muon and a neutralino (chargino), which will then decay into a second muon and at least two jets. The analysis is based on the 2016 data set of proton-proton collisions at recorded with the CMS detector at the LHC, corresponding to an integrated luminosity of 35.

Search for dark matter produced in association with a Higgs boson decaying to a pair of bottom quarks in proton-proton collisions at .

A search for dark matter produced in association with a Higgs boson decaying to a pair of bottom quarks is performed in proton-proton collisions at a center-of-mass energy of 13 collected with the CMS detector at the LHC. The analyzed data sample corresponds to an integrated luminosity of 35.9 .

Measurement of exclusive photoproduction from protons in Pb collisions at .

The exclusive photoproduction of meson states from protons, (with ), is studied in ultraperipheral Pb collisions at a centre-of-mass energy per nucleon pair of . The measurement is performed using the decay mode, with data collected by the CMS experiment corresponding to an integrated luminosity of 32.6 .

Uncultured Microbial Phyla Suggest Mechanisms for Multi-Thousand-Year Subsistence in Baltic Sea Sediments.

Energy-starved microbes in deep marine sediments subsist at near-zero growth for thousands of years, yet the mechanisms for their subsistence are unknown because no model strains have been cultivated from most of these groups. We investigated Baltic Sea sediments with single-cell genomics, metabolomics, metatranscriptomics, and enzyme assays to identify possible subsistence mechanisms employed by uncultured , , group OPB41, , , , , , and marine group II lineages. Some functions appeared to be shared by multiple lineages, such as trehalose production and NAD-consuming deacetylation, both of which have been shown to increase cellular life spans in other organisms by stabilizing proteins and nucleic acids, respectively.

Measurement of associated production of a boson and a charm quark in proton-proton collisions at .

Measurements are presented of associated production of a boson and a charm quark ( ) in proton-proton collisions at a center-of-mass energy of 13 . The data correspond to an integrated luminosity of 35.7 collected by the CMS experiment at the CERN LHC.

Characterization of the Interactive Effects of Labile and Recalcitrant Organic Matter on Microbial Growth and Metabolism.

Geochemical models typically represent organic matter (OM) as consisting of multiple, independent pools of compounds, each accessed by microorganisms at different rates. However, recent findings indicate that organic compounds can interact within microbial metabolisms. The relevance of interactive effects within marine systems is debated and a mechanistic understanding of its complexities, including microbe-substrate relationships, is lacking.

Evaluation of two vaginal, uterus sparing operations for pelvic organ prolapse: modified Manchester operation (MM) and sacrospinous hysteropexy (SSH), a study protocol for a multicentre randomized non-inferiority trial (the SAM study).

Background: Pelvic organ prolapse (POP) affects up to 40% of parous women which adversely affects the quality of life. During a life time, 20% of all women will undergo an operation. In general the guidelines advise a vaginal operation in case of uterine descent: hysterectomy with uterosacral ligament plication (VH), sacrospinous hysteropexy (SSH) or a modified Manchester operation (MM).

Search for Narrow Hγ Resonances in Proton-Proton Collisions at sqrt[s]=13 TeV.

A search for heavy, narrow resonances decaying to a Higgs boson and a photon (Hγ) has been performed in proton-proton collision data at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 35.9  fb^{-1} collected with the CMS detector at the LHC in 2016. Events containing a photon and a Lorentz-boosted hadronically decaying Higgs boson reconstructed as a single, large-radius jet are considered, and the γ+jet invariant mass spectrum is analyzed for the presence of narrow resonances.

Search for rare decays of and Higgs bosons to and a photon in proton-proton collisions at = 13 .

A search is presented for decays of and Higgs bosons to a meson and a photon, with the subsequent decay of the to . The analysis uses data from proton-proton collisions with an integrated luminosity of 35.9 at collected with the CMS detector at the LHC.

Study of the underlying event in top quark pair production in collisions at 13 .

Measurements of normalized differential cross sections as functions of the multiplicity and kinematic variables of charged-particle tracks from the underlying event in top quark and antiquark pair production are presented. The measurements are performed in proton-proton collisions at a center-of-mass energy of 13 , and are based on data collected by the CMS experiment at the LHC in 2016 corresponding to an integrated luminosity of 35.9 .

Search for single production of vector-like quarks decaying to a top quark and a boson in proton-proton collisions at .

A search is presented for the single production of vector-like quarks in proton-proton collisions at . The data, corresponding to an integrated luminosity of 35.9 , were recorded with the CMS experiment at the LHC.

Participation and Ease of Use in Colorectal Cancer Screening: A Comparison of 2 Fecal Immunochemical Tests.

Introduction: The impact of fecal immunochemical test (FIT)-based colorectal cancer (CRC) screening on disease incidence and mortality is affected by participation, which might be influenced by ease of use of the FIT. We compared the participation rates and ease of use of 2 different FITs in a CRC screening program.

Methods: There were two study designs within the Dutch CRC screening program.