Chronic conditions and multimorbidity in a primary care population: a study in the Swiss Sentinel Surveillance Network (Sentinella).

Objectives: To provide estimates of the prevalence of chronic conditions in Swiss primary care.

Methods: In total, 175 general practitioners (GP) or pediatricians (PED) reporting to the Swiss Sentinel Surveillance Network collected morbidity data.

Results: In 26,853 patient contacts, mean (± SD) age was 55.

Medication incidents in primary care medicine: a prospective study in the Swiss Sentinel Surveillance Network ().

Objectives: To describe the type, frequency, seasonal and regional distribution of medication incidents in primary care in Switzerland and to elucidate possible risk factors for medication incidents.

Design: Prospective surveillance study.

Setting: Swiss primary healthcare, Swiss Sentinel Surveillance Network.

Medication incidents in primary care medicine: protocol of a study by the Swiss Federal Sentinel Reporting System.

Background/rationale: Patient safety is a major concern in healthcare systems worldwide. Although most safety research has been conducted in the inpatient setting, evidence indicates that medical errors and adverse events are a threat to patients in the primary care setting as well. Since information about the frequency and outcomes of safety incidents in primary care is required, the goals of this study are to describe the type, frequency, seasonal and regional distribution of medication incidents in primary care in Switzerland and to elucidate possible risk factors for medication incidents.

Preoperative factors predicting clinical outcome following laparoscopic fundoplication.

Background: Antireflux surgery is effective for the treatment of gastroesophageal reflux, but not all patients benefit equally from it. The challenge is to identify the patients who will ultimately benefit from antireflux surgery. The aim of this study was to identify preoperative factors that predict clinical outcome after antireflux surgery, with special interest in the influence of socioeconomic factors.

Ultrastructural localization of the maltose-binding protein within the cell envelope of Escherichia coli.

Logarithmically growing cells of Escherichia coli were fixed with glutaraldehyde and incubated with antimaltose-binding protein Fab coupled to horseradish peroxide (molecular weight of the complex 80,000). The position of this complex within the cell envelope was determined by reacting with diaminobenzidine-H2O2, staining with osmium tetroxide and processing for thin section electron microscopy. The following observations were made: (i) induction of the maltose-binding protein resulted in swelling and staining of the outer membrane; (ii) the swelling and staining was more prominent in short cells, less prominent or absent in long cells; (iii) rare examples exhibited granular staining in the space between the plasma membrane and the peptidoglycan layer.

[Treatment possibilities of arterial circulatory disorders using calcitonin].

74 patients with arterial circulatory disorders have been treated with calcitonin in low dosages (0.25-0.5 mg s.

[Treatment of the painful Paget's disease of the pelvis with salmon calcitonin in ambulant care. Studies in 2 cases during 26 and 19 months respectively].

Two patients with Paget's disease of the bones have been treated with salmon calcitonin for periods of 19 and 26 months. The results are good.