The relationship of dietary fat to atherosclerotic disease.

Atherosclerosis is the Number One public health problem. Many factors have been implicated in the pathogenesis of this disease. Prominent among these factors is the amount and kind of fat in the diet.

Treatment of diabetic patients; observations on the use of carbutamide and tolbutamide.

Of a group of 32 patients with diabetes, 26 had a favorable modification of the disease in response to administration of butyl-sulfonyl-urea. All but one of the patients who had good response were past the age of 38. All diabetic patients included in this group were those with little or no tendency to ketosis after cessation of insulin administration.