Barriers to early detection: Insurance denials for breast MRI screening in women with germline BRCA1/2 mutations.

Objectives: Women with germline BRCA1/2 pathogenic variants (gBRCA1/2) are recommended to undergo annual breast MRI and mammography. Our objective was to describe the frequency of insurance denials for annual breast MRIs in women with gBRCA1/2 and determine denial trends.

Methods: Women with gBRCA1/2 following in a high-risk breast cancer clinic with breast MRIs ordered from 2020 to 2021 were identified and cross-referenced with a database of insurance denials.

Impact of Financial Toxicity on Treatment Adherence and Quality of Life in Pancreatic Cancer.

Purpose: Financial toxicity (FT) is increasingly recognized as a major issue in cancer care. We evaluated the prevalence and risk factors for FT in patients with pancreatic ductal adenocarcinoma (PDAC) and FT associations with treatment adherence and quality of life (QOL).

Methods: A screening questionnaire based on the Comprehensive Score for Financial Toxicity (COST) was implemented at our National Cancer Institute-designated comprehensive cancer center.

Development of myopia in scuba diving and hyperbaric oxygen treatment: a case report and systematic review.

Introduction: A 54-year-old, previously healthy Caucasian male diver was on a 22-day liveaboard diving holiday. During this time, he performed 75 open-circuit dives, of which 72 were with enriched air nitrox. All dives were within recreational length and depth.

Distal biceps tendon repair: outcome and complications with single incision anchor fixation.

Purpose: The purpose of this study is to evaluate the functional outcome and quality of life in distal biceps tendon repair with single incision technique and anchor fixation method.

Methods: A retrospective cohort study was made of patients with complete distal biceps tendon rupture. The chosen repair method was single incision technique with anchor fixation.

Distal biceps tendon rupture: a comprehensive overview.

Distal biceps tendon (DBT) is a relatively rare injury mainly occurring in middle-aged men while in eccentric biceps muscle contraction. Clinical appearance with proximal avulsion of the muscle and specific clinical tests are most of the time sufficient for diagnosing DBT, but if needed ultrasonography and MRI, most often in FABS view, can be used to ensure diagnosis of DBT and partial DBT. Surgical anatomical reinsertion has shown to be a successful method of treatment, although conservative treatment can be initiated in older patients.

Financial Toxicity Order Set: Implementing a Simple Intervention to Better Connect Patients With Resources.

Purpose: Financial toxicity of cancer treatment is well described in the literature, including characterizations of its risk factors, manifestations, and consequences. There is, however, limited research on interventions, particularly those at the hospital level, to address the issue.

Methods: From March 1, 2019, to February 28, 2022, a multidisciplinary team conducted a three-cycle Plan-Do-Study-Act (PDSA) process to develop, test, and implement an electronic medical record (EMR) order set to directly refer patients to a hospital-based financial assistance program.

Delayed treatment for decompression illness: factors associated with long treatment delays and treatment outcome.

Introduction: Effectiveness of delayed hyperbaric oxygen treatment (HBOT) for decompression illness (DCI) and factors affecting treatment delays have not been studied in large groups of patients.

Methods: This retrospective study included 546 DCI patients treated in Finland in the years 1999-2018 and investigated factors associated with recompression delay and outcome. Treatment outcome was defined as fully recovered or presence of residual symptoms on completion of HBOT.

Association Between Remote Monitoring and Acute Care Visits in High-Risk Patients Initiating Intravenous Antineoplastic Therapy.

Purpose: Traditional oncology care models have not effectively identified and managed at-risk patients to prevent acute care. A next step is to harness advances in technology to enable patients to report symptoms any time, enabling digital hovering-intensive symptom monitoring and management. Our objective was to evaluate a digital platform that identifies and remotely monitors high-risk patients initiating antineoplastic therapy with the goal of preventing acute care visits.

Decompression illness in Finnish technical divers: a follow-up study on incidence and self-treatment.

Introduction: Technical diving is increasing in popularity in Finland, and therefore the number of decompression illness (DCI) cases is also increasing among technical divers. Although hyperbaric oxygen treatment (HBOT) remains the standard of care, there are anecdotal reports of technical divers treating mild DCI symptoms themselves and not seeking a medical evaluation and possible recompression therapy. This study aimed to make an epidemiologic inventory of technical diving-related DCI symptoms, to establish the incidence of self-treatment and to determine the apparent effectiveness of different treatment methods.

Firefighters' feet: Differences by sex and weight-bearing.

Firefighters have reported their protective boots to be bulky and ill-fitting, which they believe restrict the lower body movement on the unpredictable fireground. This study used 3D foot scanning to compare the shape of firefighters' feet to the general population, the shape of female firefighters' feet to males, and the impact of the heavy fire gear on foot shape. The results found the foot breadth of firefighters was larger than the general population and the feet of female firefighters were slimmer than males.

Analysis of a Remote Monitoring Program for Symptoms Among Adults With Cancer Receiving Antineoplastic Therapy.

Importance: Electronic patient-reported outcomes (ePROs) may have the potential to improve cancer care delivery by enhancing patient quality of life, reducing acute care visits, and extending overall survival. However, the optimal cadence of ePRO assessments is unknown.

Objective: To determine patient response preferences and the clinical value associated with a daily cadence for ePROs for patients receiving antineoplastic treatment.

Risk factors for financial toxicity in patients with gynecologic cancer.

Background: The cost of cancer care is high and rising. Evidence of increased patient cost burden is prevalent in the medical literature and has been defined as "financial toxicity," the financial hardship and financial concerns experienced by patients because of a disease and its related treatments. With targeted therapies and growing out-of-pocket costs, patient financial toxicity is a growing concern among patients with gynecologic cancer.

Understanding firewomen's fit problems with their coats and pants and its impact on mobility and safety.

Background: Inadequately fitting turnout coats and pants hamper mobility and safety of firewomen. Previous research has established that firewomen are dissatisfied with their turnout coats and pants. Yet, there has been minimal in-depth research into the specific fit problems and consequences of these problems on the workplace health of firewomen.

InSight Care Pilot Program: Redefining Seeing a Patient.

Purpose: Early detection and management of symptoms in patients with cancer improves outcomes. However, the optimal approach to symptom monitoring and management is unknown. InSight Care is a mobile health intervention that captures symptom data and facilitates patient-provider communication to mitigate symptom escalation.

Amphiphilic Dimers at Liquid-Liquid Interfaces: A Density Functional Approach.

We apply density functional theory to study the structure of dimers at the interface between two partially miscible symmetric liquids. The dimers are built of two tangentially jointed spheres and do not solve the coexisting liquids. The interactions in the system are modeled using Lennard-Jones potentials with different interactions between segments of the dimers and the liquid components.

Density functional approach to the description of the structure of dimer nanoparticles at liquid-liquid interfaces.

An extension of the density functional approach from our recent work (Phys. Chem. Chem.

Janus Dimers at Liquid-Liquid Interfaces.

We study the impact of selected parameters on the behavior of Janus-like dimers at liquid-liquid interface. The equilibrium orientation and the adsorption depth of a single Janus dimer are calculated using a simple phenomenological method. We have also performed molecular dynamics simulations for different numbers of Janus dimers trapped at the interface between two partially miscible Lennard-Jones fluids.

Density functional theory for the microscopic structure of nanoparticles at the liquid-liquid interface.

We propose an extension of the density functional approach to study the structure and thermodynamic properties of a system comprising a certain amount of nanoparticles at the interface between two partially miscible liquids. Model calculations have been carried out for a binary symmetric mixture of Yukawa fluids and hard-sphere nanoparticles. Despite its simplicity, the model captures the principal features of this type of system.

Towards the description of adsorption of water in slit-like pores with walls covered by molecular brushes.

The density profiles, adsorption isotherms, and phase behavior of a water model in a slit-like pore with walls modified by pre-adsorbed tethered chain molecules have been studied in the framework of a density functional theory. Each chain is bonded to the surface by its terminal segment, and the surface density of grafted chains is the same for each wall. The model for water taken from the work of Clark [Mol.

Adsorption and phase behavior of water-like fluid models with square-well attraction and site-site association in slit-like pores: Density functional approach.

The adsorption and phase behavior of two model fluids, both with square well inter-particle attraction and site-site associative interaction, in slit-like pores have been studied in the framework of a density functional theory. The mean field approach and the first-order mean spherical approximation have been applied to account for the attractive interactions. The chemical association effects are taken into account by using the first-order thermodynamic perturbation theory of Wertheim.

Misery Loves Company: Presenting Symptom Clusters to Urgent Care by Patients Receiving Antineoplastic Therapy.

Purpose: The Centers for Medicare & Medicaid Services (CMS) identifies suboptimal management of treatment toxicities as a care gap and proposes the measurement of hospital performance on the basis of emergency department visits for 10 common symptoms. Current management strategies do not address symptom co-occurrence.

Methods: We evaluated symptom co-occurrence in three patient cohorts that presented to a cancer hospital urgent care center in 2016.

Gelation of patchy ligand shell nanoparticles decorated by liquid-crystalline ligands: computer simulation study.

We consider the coarse-grained modelling of patchy ligand shell nanoparticles with liquid crystalline ligands. The cases of two, three, four and six symmetrically arranged patches of ligands are discussed, as well as the cases of their equatorial and icosahedral arrangement. A solution of decorated nanoparticles is considered within a slit-like pore with solid walls and the interior filled by a polar solvent.