Publications by authors named "SNYDER B"

Article Synopsis
  • The study reports new county records for 13 counties in Georgia based on collections from the Georgia Museum of Natural History and the authors.
  • Eight species are identified as new state records, including Amynthas carnosus and Metaphire hilgendorfi.
  • An updated checklist for Middle Georgia is provided, enhancing previous data compiled by Reynolds in 2015.
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Preparation of athletes to begin a competition or enter mid-competition with the ability to reach peak performance immediately may be partly dependent on the efficacy of the warmup protocol. Previous research on flexible barbells reported significant differences in muscle activation when compared to steel barbells. The manufacturers of handheld flexible bars with a combined weight of 3.

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Introduction: Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic condition characterized by premature aging, impacting multiple organ systems, including cardiovascular, musculoskeletal, and integumentary. Significant abnormalities in a transgenic mouse model (homozygous G608G mutation), specifically targeting the development of skull and facial bone indices through high-resolution CT scanning and cephalometric analysis.

Methods: Key measurements include bone thickness, skull volume, and cranial suture integrity.

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Article Synopsis
  • The study investigates the effect of low-magnitude mechanical signals (LMMS) on preserving bone mineral density (BMD) in malnourished adolescents and young adults with anorexia nervosa over a 6-month period.
  • A total of 837 female adolescents were screened, with 317 qualifying for the trial, and 40 participants completed it, using a placebo-controlled approach for the intervention.
  • Results showed no significant changes in total volumetric BMD between the LMMS and placebo groups, though some positive changes were observed in cross-sectional area at the tibia site in the LMMS group.
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Objective: We aimed to develop an algorithm that accurately identifies children with Down syndrome (DS) using administrative data.

Methods: We identified a cohort of children born between 2000 and 2017, enrolled in the Tennessee Medicaid Program (TennCare), who either had DS coded on their birth certificate or had a diagnosis listed using an International Classification of Diseases (ICD) code (suspected DS), and who received care at Vanderbilt University Medical Center, a comprehensive academic medical center, in the United States. Children with suspected DS were defined as having DS if they had (a) karyotype-confirmed DS indicated on their birth certificate; (b) karyotype-pending DS indicated on their birth certificate (or just DS if test type was not specified) and at least two healthcare encounters for DS during the first 6 years of life; or (c) at least three healthcare encounters for DS, with the first and last encounter separated by at least 30 days, during the first six years of life.

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The transforming growth factor β (TGF-β) superfamily plays a crucial role in regulating biological processes of virtually every tissue and system in the body, including hemostasis and hematopoiesis. Elritercept (KER-050) is an investigational, modified activin receptor type IIA ligand trap designed to bind and inhibit activin A and other select TGF-β superfamily ligands, including activin B, growth differentiation factor 8 (GDF-8), and GDF-11. The objectives of this phase 1 randomized, placebo-controlled study of elritercept were to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamic markers of activin inhibition and hematopoiesis in healthy postmenopausal women (N = 48).

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In the setting of increasing patient-reported cannabidiol (CBD) usage in the dermatologic setting, it is of great importance that clinicians become aware of potential medication interactions that may arise from cannabidiol usage in order to ensure safe and efficacious medication therapy. This brief review aimed to bring awareness to the mechanism of CBD while highlighting potential interactions between CBD and medication therapy for commonly encountered dermatologic conditions, including acne, allergic contact dermatitis, atopic dermatitis, pruritus, skin aging, skin cancer, and psoriasis.

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Importance: Limited access to healthy foods, resulting from residence in neighborhoods with low food access, is a public health concern. The contribution of this exposure in early life to child obesity remains uncertain.

Objective: To examine associations of neighborhood food access during pregnancy or early childhood with child body mass index (BMI) and obesity risk.

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Introduction: Understanding the lived experience of illness is important for empowering patients and informing health care practitioners. This study investigated the impact of a book-length comic memoir, , by Peter Dunlap-Shohl, on patients' mental health, knowledge, and attitudes about living with Parkinson's disease (PD). The authors further explored which patients found the book to be beneficial and why.

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The chemokine co-receptors CXCR4 and CCR5 mediate HIV entry and signal transduction necessary for viral infection. However, to date only the CCR5 antagonist maraviroc is approved for treating HIV-1 infection. Given that approximately 50% of late-stage HIV patients also develop CXCR4-tropic virus, clinical anti-HIV CXCR4 antagonists are needed.

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Background: Anatomic total shoulder arthroplasty (aTSA) may not be an ideal treatment option for young and active patients because of potential activity restriction and concerns about glenoid loosening. The ream-and-run procedure (RnR) allows for the continuance of high-level activity without concerns of a glenoid component failure. Initial RnR publications are promising, although more outcomes studies are needed.

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Background: The contribution of prenatal anthropometric measures to the development of specific childhood asthma phenotypes is not known.

Objective: We aimed to evaluate associations between prepregnancy body mass index (BMI) and gestational weight gain (GWG) with allergic and nonallergic asthma phenotypes in childhood.

Methods: Our study population included term, healthy infants in the middle Tennessee region of the United States.

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Background And Purpose: Although the prevalence of dissociative disorders (DDs) is up to 10 percent of the general population, psychiatric-mental health (PMH) registered nurses lack education on how to care for individuals diagnosed with these disorders.

Method: Sixty-two PMH nurse educators completed an anonymous online survey about their perceptions of teaching DDs to nursing students. Braun and Clarke's six-phase framework was used to conduct an inductive, reflexive thematic analysis of the data.

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The ability of articular cartilage to withstand significant mechanical stresses during activities, such as walking or running, relies on its distinctive structure. Integrating detailed tissue properties into subject-specific biomechanical models is challenging due to the complexity of analyzing these characteristics. This limitation compromises the accuracy of models in replicating cartilage function and impacts predictive capabilities.

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Background And Objectives: Physicians have long been considered valued members of a solid US health care system. Significant changes in medical education, health care, and society at-large suggest that current medical students may face a different future. To help guide educators and policy makers, we set out to understand medical students' perceptions of the future of health care and their place in it.

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Background: Neuromuscular early-onset scoliosis (N-EOS) often presents with a long sweeping thoracolumbar scoliosis and pelvic obliquity. With severe pelvic obliquity, the ribs come into contact with the high side of the pelvis, termed rib-on-pelvis deformity (ROP). The goal of this study is to evaluate whether ROP is associated with reported pain and other health-related quality of life (HRQOL) measures.

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Despite improvements in survival, adolescent and young adult (AYA) oncology patients are at high risk for experiencing negative health-related quality of life (HRQOL) outcomes. AYA cancer programs have attempted to develop assessment tools to identify areas of need. We aimed to demonstrate the feasibility/utility of the Patient-Reported Outcome Measurement Information System-29 (PROMIS-29) within an AYA oncology program clinic.

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Background: Breast cancer (BrCa) is a predominant malignancy, with metastasis occurring in one in eight patients, nearly half of which target the bone, leading to serious complications such as pain, fractures, and compromised mobility. Structural rigidity, crucial for bone strength, becomes compromised with osteolytic lesions, highlighting the vulnerability and increased fracture risk in affected areas. Historically, two-dimensional radiographs have been employed to predict these fracture risks; however, their limitations in capturing the three-dimensional structural and material changes in bone have raised concerns.

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Article Synopsis
  • Joint kinematic instability, whether congenital or due to other health factors, leads to cartilage damage and progression to osteoarthritis (OA), which affects joint function.
  • OA reduces the effectiveness of synovial fluid lubrication, primarily due to the loss of important components like hyaluronic acid.
  • Viscosupplementation and advanced biomimetic strategies are being explored to improve joint lubrication and minimize cartilage wear, though results vary and effectiveness can be limited.
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Study Design: Modified Delphi consensus study.

Objective: To develop consensus-based best practices for the care of pediatric patients who have implanted programmable devices (IPDs) and require spinal deformity surgery.

Summary Of Background Data: Implanted programmable devices (IPDs) are often present in patients with neuromuscular or syndromic scoliosis who require spine surgery.

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Article Synopsis
  • The study investigates the potential of e-cigarettes (ECs) to aid pregnant smokers in quitting combustible cigarettes (CCs) and evaluates the characteristics of users who switch to ECs.
  • Approximately 1.5% of pregnant smokers reported using ECs, with around 29.7% of them becoming exclusive EC users; EC initiators tended to have lower socioeconomic status and less access to prenatal care.
  • Findings suggest that while some pregnant smokers who switch to ECs may reduce their CC usage, there is no evidence that this leads to significant health benefits for neonates, indicating that ECs may not be an effective strategy for smoking cessation during pregnancy.
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Article Synopsis
  • The HEROS Study is a prospective, multicity research effort conducted from May 2020 to February 2021, aimed at understanding risk factors for SARS-CoV-2 infection and transmission, particularly among children and those with asthma or allergies.
  • The study utilized remote methods to enroll participants, who completed weekly surveys and nasal sampling, allowing researchers to gather data without in-person visits during the pandemic.
  • A total of 5598 individuals were involved, ensuring a comprehensive household-based analysis of infection and transmission dynamics related to COVID-19.
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Cationic contrast-enhanced computed tomography (CECT) capitalizes on increased contrast agent affinity to the charged proteoglycans in articular cartilage matrix to provide quantitative assessment of proteoglycan content with enhanced images. While high resolution microCT has demonstrated success, we investigate cationic CECT use in longitudinal in vivo imaging at clinical resolution. We hypothesize that repeated administration of CA4+ will have no adverse side effects or complications, and that sequential in vivo imaging assessments will distinguish articular cartilage repair tissue from early degenerative and healthy cartilage in critically sized chondral defects.

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