America's Opioid Ecosystem: How Leveraging System Interactions Can Help Curb Addiction, Overdose, and Other Harms.

Opioids play an outsized role in America's drug problems, but they also play a critically important role in medicine. Thus, they deserve special attention. Illegally manufactured opioids (such as fentanyl) are involved in a majority of U.

Redirecting Innovation in U.S. Health Care: Options to Decrease Spending and Increase Value.

New medical technologies are a leading driver of U.S. health care spending.

Challenges to Value-Enhancing Innovation in Health Care Delivery: Commonalities and Contrasts with Innovation in Drugs and Devices.

Limiting the growth of health care costs while improving population health is perhaps the most important and difficult challenge facing U.S. health policymakers.