[Are lysosomal enzymes involved in regulation of cell proliferation? (AUTHOR'S TRANSL)].

An activation of cell growth is affected by the addition of proteolytic enzymes to cultures of normal cells. A stimulation of integration of thymidine or guanosine into the nucleic acids, and a phosphorylation of histones resulted after protease treatment of cells and also of resulted after protease treatment of cells and also of isolated nuclei. Proteases are present in the lysosomes, among them also some whose maximal activity is in the region of pH 7.