Publications by authors named "SCHERER I"

Purpose: To identify and assess any changes in the pulp tissue complex following orthodontic force application.

Materials And Methods: Published and unpublished literature was searched in seven databases until 9 August 2022 for randomised controlled trials (RCTs) and prospective trials (nR-PCT). Representative key words included 'pulp response', 'pulp tissue', 'orthodontic force', and 'tooth movement'.

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Article Synopsis
  • Recent studies indicate a growing global threat from multidrug-resistant pathogens, particularly Stenotrophomonas maltophilia, which poses risks to healthcare settings.
  • An international analysis of this pathogen revealed it is divided into 23 distinct lineages, many of which contain strains capable of varying levels of human virulence.
  • Notably, lineage Sm6 was found to have the highest association with human infections and includes key genes linked to virulence and antibiotic resistance, suggesting potential for hospital outbreaks among closely related strains.
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  • Rats subjected to a 3-hour daily restraint for three days experience significant weight loss that does not fully recover after the restraint ends.
  • Administering corticosterone to adrenalectomized (ADX) rats mimics the weight loss seen in intact restrained rats, suggesting corticosterone's key role in this process.
  • The study indicates that the mechanism behind corticosterone-induced weight loss in ADX rats is distinct from changes in certain brain mRNA expressions, implying other pathways are involved in the body’s response to stress and weight regulation.
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