Deep mantle earthquakes linked to CO degassing at the mid-Atlantic ridge.

Volatiles (CO, HO) play a fundamental role in mantle melting beneath ocean spreading centers, but what role they play during the melt migration remains unknown. Using seismological data recorded by ocean-bottom seismometers, here we report the presence of deep earthquakes at 10-20 km depth in the mantle along the Mid-Atlantic Ridge axis, much below the brittle-ductile boundary. Syntheses of regional basaltic rock samples and their geochemical analyses indicate the presence of an abnormally high quantity of CO (~0.

A randomized, double-blinded, placebo-controlled, single-center, comparative study evaluating Phaseolean® safety and efficacy in overweight/obese participants.

Scope: Phaseolean®, a standardized water extract of or white kidney bean, exhibits α-amylase inhibitory property, which decreases calorie absorption by preventing or delaying carbohydrate digestion, thus supporting weight management. This randomized, double-blind, placebo-controlled, single-center comparative study (Clinical trial registration number: CTRI/2023/02/049440, Registered on: February 03, 2023) evaluated the safety and efficacy of Phaseolean® in weight management in overweight or obese participants upon regular intake at two different doses compared with placebo.

Method: Sixty-six participants were enrolled and randomly divided into three groups, considering the inclusion & exclusion criteria.

Bacteria-mediated green synthesis of silver nanoparticles and their antifungal potentials against Aspergillus flavus.

The best biocontroller Bacillus subtilis produced silver nanoparticles (AgNPs) with a spherical form and a 62 nm size through green synthesis. Using UV-vis spectroscopy, PSA, and zeta potential analysis, scanning electron microscopy, and Fourier transform infrared spectroscopy, the properties of synthesized silver nanoparticles were determined. Silver nanoparticles were tested for their antifungicidal efficacy against the most virulent isolate of the Aspergillus flavus fungus, JAM-JKB-BHA-GG20, and among the 10 different treatments, the treatment T6 [PDA + 1 ml of NP (19: 1)] + Pathogen was shown to be extremely significant (82.

Drug resistant epilepsy and ketogenic diet: A narrative review of mechanisms of action.

Drug-resistant epilepsy (DRE) poses a significant global challenge, impacting the well-being of patients. Anti-epileptic drugs often fail to effectively control seizures in individuals with DRE. This condition not only leads to persistent seizures but also induces neurochemical imbalances, elevating the risk of sudden unexpected death in epilepsy and comorbidities.

Prevalence of human papillomavirus infection and associated factors among women attending cervical cancer screening in setting of Addis Ababa, Ethiopia.

Human papillomaviruses (HPVs) are circular, nonenveloped small double-stranded DNA viruses that infect stratified epithelium and can cause a number of life-threatening diseases. HPV is the central risk factor for developing cervical cancer and is estimated that approximately 98% of this disease is associated with oncogenic types of HPV. HPV infection leads to an estimated 266,000 cervical cancer deaths annually.

Whole genome sequencing and annotation of Aspergillus flavus JAM-JKB-B HA-GG20.

Groundnuts are mostly contaminated with the mold Aspergillus flavus which produces a carcinogenic mycotoxin called as aflatoxin. It is very important to understand the genetic factors underlying its pathogenicity, regulation, and biosynthesis of secondary metabolites and animal toxicities, but it still lacks useful information due to certain gaps in the era of modern technology. Therefore, the present study was considered to determine the key genes and metabolites involved in the biosynthesis of aflatoxin by using a molecular approach in a virulent strain of Aspergillus.

Insights into dike nucleation and eruption dynamics from high-resolution seismic imaging of magmatic system at the East Pacific Rise.

Models of magmatic systems suggest that the architecture of crustal magma bodies plays an important role in where volcanic eruptions occur, but detailed field observations are needed to evaluate them. We present ultrahigh-resolution reflection images of magma bodies beneath a region of multiple eruptions along the East Pacific Rise derived from three-dimensional seismic surveying. The observations reveal magma bodies with elongate ridges and troughs vertically aligned with seafloor eruptive fissures that we interpret as remnant dike root zones where repeat dikes nucleate.

De novo transcriptome sequencing of drought tolerance-associated genes in little millet (Panicum sumatrense L.).

The genome size of the little millet Panicum sumatrense is unknown, although its genome is fairly diploid (2n = 4x = 36). Despite tremendous nutritional value and adaptability to adverse climatic conditions, P. sumatrense use was limited by their low palatability, coarse grain, and lack of variety of culinary preparations.

Broad fault zones enable deep fluid transport and limit earthquake magnitudes.

Constraining the controlling factors of fault rupture is fundamentally important. Fluids influence earthquake locations and magnitudes, although the exact pathways through the lithosphere are not well-known. Ocean transform faults are ideal for studying faults and fluid pathways given their relative simplicity.

Resilience and Mitigation Strategies of Cyanobacteria under Ultraviolet Radiation Stress.

Ultraviolet radiation (UVR) tends to damage key cellular machinery. Cells may adapt by developing several defence mechanisms as a response to such damage; otherwise, their destiny is cell death. Since cyanobacteria are primary biotic components and also important biomass producers, any drastic effects caused by UVR may imbalance the entire ecosystem.

Nature-Inspired Surface Engineering for Efficient Atmospheric Water Harvesting.

Atmospheric water harvesting is a sustainable solution to global water shortage, which requires high efficiency, high durability, low cost, and environmentally friendly water collectors. In this paper, we report a novel water collector design based on a nature-inspired hybrid superhydrophilic/superhydrophobic aluminum surface. The surface is fabricated by combining laser and chemical treatments.

Controlling basal plane sulfur vacancy in water splitting MoSx/NiF electrocatalysts through electric-field-assisted pulsed laser ablation.

Eco-friendly, efficient, and durable electrocatalysts from earth-abundant materials are crucial for water splitting through hydrogen and oxygen generation. However, available methods to fabricate electrocatalysts are either hazardous and time-consuming or require expensive equipment, hindering the large-scale, eco-friendly production of artificial fuels. Here, we present a rapid, single-step method for producing MoS/NiF electrocatalysts with controlled sulfur-vacancies via electric-field-assisted pulsed laser ablation (EF-PLA) in liquid and deposition on nickel foam, enabling efficient water splitting.

Therapeutic Strategies against Biofilm Infections.

A biofilm is an aggregation of surface-associated microbial cells that is confined in an extracellular polymeric substance (EPS) matrix. Infections caused by microbes that form biofilms are linked to a variety of animals, including insects and humans. Antibiotics and other antimicrobials can be used to remove or eradicate biofilms in order to treat infections.

Hemodynamic changes in pregnancy: does central blood pressure have any role?

Pregnancy is associated with alteration in the hemodynamic state. In clinical practice, only peripheral blood pressure is measured; however, central blood pressure is a better predictor of cardiovascular events. We have investigated variations in peripheral blood pressure, central blood pressure, and augmentation index in healthy non-pregnant and pregnant women.

Seismic evidence for uniform crustal accretion along slow-spreading ridges in the equatorial Atlantic Ocean.

The crustal accretion along mid-ocean ridges is known to be spreading-rate dependent. Along fast-spreading ridges, two-dimensional sheet-like mantle upwelling creates relatively uniform crust. In contrast, the crust formed along slow-spreading ridges shows large along-axis thickness variations with thicker crust at segment centres, which is hypothesised to be due a three-dimensional plume-like mantle upwelling or due to focused melt migration to segment centres.

Gender Diverse Autistic Young Adults: A Mental Health Perspective.

Gender diverse autistic young adults often face mental health challenges which can increase the challenge of obtaining gender-affirming care. Social and communication differences associated with autism compounds the already complex process of navigating a path toward gender affirmation for individuals with these intersecting identities. In this case series of four gender diverse autistic adults, we demonstrate that success in management of their mental health crises was achieved through enlisting family and social support, obtaining effective mental health treatment, and accessing gender-affirming healthcare.

Prevalence of Entamoeba histolytica among schoolchildren in Dilla town, Gedeo zone, Ethiopia.

Background: To measure the prevalence of Entamoeba histolytica (E. histolytica) infections and associated risk factors among schoolchildren in Dilla town, Gedeo zone Ethiopia.

Methods: A total of 501 schoolchildren were recruited by random sampling.

Prevalence and associated risk factors of infection among school children from three primary schools in Arsi Town, West Zone, Ethiopia.

is one of the major pathogenic intestinal parasites and is amongst the leading causes of diarrheal illness in children. Around 500 million people are infected worldwide, while 75,000 die of the disease annually. is associated with moderate to severe diarrhoea and increased mortality among children in African countries and negatively affects child growth and development.

Exploration of Novel Lichen Compounds as Inhibitors of SARS-CoV-2 Mpro: Ligand-Based Design, Molecular Dynamics, and ADMET Analyses.

In the year 2019-2020, the whole world witnessed the spread of a disease called COVID-19 caused by SARS-CoV-2. A number of effective drugs and vaccine has been formulated to combat this outbreak. For the development of anti-COVID-19 drugs, the main protease (Mpro) is considered a key target as it has rare mutations and plays a crucial role in the replication of the SARS CoV-2.

Evolution of the Crustal and Upper Mantle Seismic Structure From 0-27 Ma in the Equatorial Atlantic Ocean at 2° 43'S.

We present seismic tomographic results from a unique seismic refraction and wide-angle survey along a 600 km long flow-line corridor of oceanic lithosphere ranging in age from 0 to 27 Ma in the equatorial Atlantic Ocean at 2° 43'S. The velocities in the crust near the ridge axis rapidly increase in the first 6 Myr and then change gradually with age. The upper crust (Layer 2) thickness varies between 2 and 2.

Lower oceanic crust formed by in situ melt crystallisation revealed by seismic layering.

Oceanic crust forms at mid-ocean spreading centres through a combination of magmatic and tectonic processes, with the magmatic processes creating two distinct layers: the upper and the lower crust. While the upper crust is known to form from lava flows and basaltic dikes based on geophysical and drilling results, the formation of the gabbroic lower crust is still debated. Here we perform a full waveform inversion of wide-angle seismic data from relatively young (7-12-million-year-old) crust formed at the slow spreading Mid-Atlantic Ridge.