Engineered Osteochondral Scaffolds with Bioactive Cartilage Zone for Enhanced Articular Cartilage Regeneration.

Despite progress, osteochondral (OC) tissue engineering strategies face limitations in terms of articular cartilage layer development and its integration with the underlying bone tissue. The main objective of this study is to develop a zonal OC scaffold with native biochemical signaling in the cartilage zone to promote articular cartilage development devoid of cells and growth factors. Herein, we report the development and in vivo assessment of a novel gradient and zonal-structured scaffold for OC defect regeneration.

Effect of Sr substitution on the structural, dielectric and ferroelectric property of BaTiO.

We have performed a comprehensive study to explore the effect of Sr substitution on the structural and ferroelectric properties of BaTiO(BTO) with compositions BaSrTiOfor 0 ⩽⩽ 1. The room temperature structural investigation inferred that the samples with compositions> 0.30 has cubic phase instead of tetragonal as for pristine BTO.

Evidence of Strong Orbital-Selective Spin-Orbital-Phonon Coupling in CrVO_{4}.

Coupling of orbital degree of freedom with a spin exchange, i.e., Kugel-Khomskii-type interaction (KK), governs a host of material properties, including colossal magnetoresistance, enhanced magnetoelectric response, and photoinduced high-temperature magnetism.

Decellularized extracellular matrix biomaterials for regenerative therapies: Advances, challenges and clinical prospects.

Tissue engineering and regenerative medicine have shown potential in the repair and regeneration of tissues and organs via the use of engineered biomaterials and scaffolds. However, current constructs face limitations in replicating the intricate native microenvironment and achieving optimal regenerative capacity and functional recovery. To address these challenges, the utilization of decellularized tissues and cell-derived extracellular matrix (ECM) has emerged as a promising approach.

Bilateral Flexor Digitorum Accessorius Longus Precipitating Bilateral Tarsal Tunnel Syndrome: A Case Report.

Case: A 29-year-old woman presented with bilateral tarsal tunnel syndrome caused by bilateral flexor digitorum accessorius longus, experiencing immediate relief of symptoms after surgical intervention through 1 year.

Conclusion: Accessory muscles can cause compressive neuropathies in multiple areas of the body. In patients who have FDAL as the cause of their tarsal tunnel syndrome, surgeons should have a high index of suspicion of bilateral FDAL if the same patient develops similar contralateral symptoms.

A Thrifty Liquid-Phase Exfoliation (LPE) of MoSe and WSe Nanosheets as Channel Materials for FET Application.

Two-dimensional materials are trending nowadays because of their atomic thickness, layer-dependent properties, and their fascinating application in the semiconducting industry. In this work, we have synthesized MoSe and WSe nanosheets (NSs) via a liquid-phase exfoliation method and investigated these NSs as channel materials in field-effect transistors (FET). The x-ray diffraction (XRD) pattern revealed that the synthesized NSs have a 2H phase with 0.

A single-step plasma method for rapid production of 2D, ferromagnetic, surface vacancy-engineered MoOnanomaterials, for photothermal ablation of cancer.

A rapid, clean plasma-chemical technique is demonstrated here, for cost-effective, synthesis of surface vacancy engineered, 2D, molybdenum-oxide nanomaterials, during a one-step, integrated synthesis-hydrogenation process for biomedical applications. A laminar plasma beam populated with O and H radicals impinges on a molybdenum target, out of which molybdenum-oxide nanomaterials are very rapidly generated with controlled surface O vacancies. 2D, dark-blue coloured, nano-flake/ribbon like MoOis produced maximum up to 194 g h, the core of which still remains as stoichiometric molybdenum-oxide.

Optical temperature sensing by tuning photoluminescence in a wide (visible to near infrared) wavelength range in a Eu-doped Bi-based relaxor ferroelectric.

The prevalent material design principles for optical thermometry primarily rely on thermally driven changes in the relative intensities of the thermally coupled levels (TCLs) of rare-earth-doped phosphor materials, where the maximum achievable sensitivity is limited by the energy gap between the TCLs. In this work, a new, to the best of our knowledge, approach to thermometric material design is proposed, which is based on temperature tuning of PL emission from the visible to the NIR region. We demonstrate a model ferroelectric phosphor, Eu-doped 0.

Lattice assisted dielectric relaxation in four-layer Aurivillius BiFeTiOceramic at low temperatures.

We have investigated magnetic, structural and dielectric properties of BiFeTiO(BFTO) in the temperature range 5K-300 K. Using diffraction, Raman spectroscopy and x-ray absorption fine structure measurements, iso-structural modifications are observed at low temperatures (≈100 K). The analysis of dielectric constant data revealed signatures of dielectric relaxation, concomitant with these structural modifications in BFTO at the same temperatures.

Amorphous Salts Solid Dispersions of Celecoxib: Enhanced Biopharmaceutical Performance and Physical Stability.

Numerous amorphous solid dispersion (ASD) formulations of celecoxib (CEL) have been attempted for enhancing the solubility, dissolution rate, and in vivo pharmacokinetics via high drug loading, polymer combination, or by surfactant addition. However, physical stability for long-term shelf life and desired in vivo pharmacokinetics remains elusive. Therefore, newer formulation strategies are always warranted to address poor aqueous solubility and oral bioavailability with extended shelf life.

Magnetoelastic coupling and spin contributions to entropy and thermal transport in biferroic yttrium orthochromite.

Direct engineering of material properties through exploitation of spin, phonon, and charge-coupled degrees of freedom is an active area of development in materials science. However, the relative contribution of the competing orders to controlling the desired behavior is challenging to decipher. In particular, the independent role of phonons, magnons, and electrons, quasiparticle coupling, and relative contributions to the phase transition free energy largely remain unexplored, especially for magnetic phase transitions.

Femtometer atomic displacement, the root cause for multiferroic behavior of CuO unearthed through polarized Raman spectroscopy.

Recently, CuO has been proposed as a potential multiferroic material with high transition temperature. Competing models based on spin current and ionic displacements are invoked to explain ferroelectricity in CuO. The theoretical model based on ionic displacement predicted very small displacement (∼10Å) along theaxis.

Correlation of dynamical disorder and oxy-ion diffusion mechanism in a Dy, W co-doped LaMoO system: an electrolyte for IT-SOFCs.

In the present attempt, a Dy, W co-doped La2Mo2O9 (LMX) system is explored to understand the order-disorder phase transition, dynamical disorder state and their influence on the oxy-ion diffusion mechanism. The X-ray diffraction study confirms the co-dopant induced suppression of the order-disorder phase transition temperature of LMX. The oxygen ion diffusion in the LMX matrix is through intrinsic oxygen vacancies.

Enhanced Thermoelectric Performance of Novel Reaction Condition-Induced BiS-Bi Nanocomposites.

This is the first report on the enhanced thermoelectric (TE) properties of novel reaction-temperature () and duration-induced BiS-Bi nanocomposites synthesized using a facile one-step polyol method. They are well characterized as nanorod composites of orthorhombic BiS and rhombohedral Bi phases in which the latter coats the former forming BiS-Bi core-shell-like structures along with independent Bi nanoparticles. A very significant observation is the systematic reduction in electrical resistivity ρ with a whopping 7 orders of magnitude (∼10) with just reaction temperature and duration increase, revealing a promising approach for the reduction of ρ of this highly resistive chalcogenide and hence resolving the earlier obstacles for its thermoelectric application potentials in the past few decades.

Structural correlations in the enhancement of ferroelectric property of Sr doped BaTiO.

The effect of Sr doping in BaTiO(BTO) with nominal compositions BaSrTiO(BSTO) have been explored on its structural, lattice vibration, dielectric, ferroelectric and electrocaloric properties. The temperature dependent dielectric results elucidate the enhancement in dielectric constant and exhibit three frequency independent transitions around 335, 250 and 185 K, which are related to different structural transitions. All these transitions occur at lower temperature as compared with pristine BTO, however; remnant electric polarization () of BSTO is much higher than in BTO.

Spin reorientation transition and coupled spin-lattice dynamics of SmDyFeO.

In this work, we have presented a solid-solution of SmDyFeOin the form of nano-particles having spin reorientation transition (SRT) at a temperature interval of 220-260 K. The lattice dynamics of SmDyFeOhave investigated by temperature-dependent x-ray diffraction and Raman spectroscopy. A negative thermal expansion at low temperatures has observed, which might be due to the interaction between Smand Fesublattice.

Miller Fisher Variant of Guillain-Barré Syndrome in a Child.

Miller Fisher syndrome (MFS), a rare form of Guillain-Barré Syndrome, presents with the classical triad of ophthalmoplegia, areflexia, and ataxia. We describe the case of a 7-year-old boy who presented with diplopia, speech difficulty, dysphagia, gait disturbance, and difficulty in eyeball movements since 5 days. On examination, the child was having ataxia, areflexia, ophthalmoplegia, drooling of saliva, dysphonia, and absent gag reflex.

A first comparison of bone histomorphometry in extant domestic horses (Equus caballus) and a Pleistocene Indian wild horse (Equus namadicus).

The microstructural features of the tissue of long bones subjected to different biomechanical stresses could be a helpful tool for a better understanding of locomotor behavior in extant and extinct mammals, including equids. However, few researches have attempted to describe the bone tissue of extinct horses. In our study, we analyze and compare the histomorphometric features of the bone tissue in extant modern horses, Equus caballus, and Equus namadicus, a Pleistocene Indian extinct wild horse.

Strain healing of spin-orbit coupling:a cause for enhanced magnetic moment in epitaxial SrRuO thin films.

Enhanced magnetic moment and coercivity in SrRuO thin films are significant issues for advanced technological usages and hence are researched extensively in recent times. Most of the previous reports on thin films with enhanced magnetic moment attributed it to the high spin state. Our magnetization results show high magnetic moment of 3.

A 0.0023 mm /ch. Delta-Encoded, Time-Division Multiplexed Mixed-Signal ECoG Recording Architecture With Stimulus Artifact Suppression.

This article demonstrates a scalable, time-division multiplexed biopotential recording front-end capable of real-time differential- and common-mode artifact suppression. A delta-encoded recording architecture exploits the power spectral density (PSD) characteristics of Electrocorticography (ECoG) recordings, combining an 8-bit ADC, and an 8-bit DAC to achieve 14 bits of dynamic range. The flexibility of the digital feedback architecture is leveraged to time-division multiplex 64 differential input channels onto a shared mixed-signal front-end, reducing channel area by 2x compared to the state-of-the-art.

Spin phonon coupling in Mn doped HoFeO compounds exhibiting spin reorientation behaviour.

An investigation has been carried out on the spin phonon coupling in a series of isostructural polycrystalline orthorhombic (Space group Pnma) compounds HoFe Mn O (x  ⩽  0.6) exhibiting spin reorientation below Néel temperature (T ), using magnetization, neutron diffraction, and Raman scattering techniques. Mn doping leads to an anomalous increase in the spin reorientation temperature (T ), shifting it close to room temperature from T ~ 60 K for x  =  0 sample, and concomitant lowering of T .