Carboxymethyl hexanoyl chitosan drop-coated simple disposable paper electrochemical sensor for quality monitoring of vanillin.

The food and pharmaceutical sectors frequently utilize vanillin (VAN), a food ingredient with a pleasing flavor and aroma. However, excessive consumption of VAN causes several health problems, including liver and kidney damage, headaches, skin conditions, nausea, and vomiting. To prevent health problems, it is crucial to identify and control the amount of VAN in food and drugs.

Hydrothermal synthesis of tungsten oxide photo/electrocatalysts: precursor-driven morphological tailoring and electrochemical performance for hydrogen evolution and oxygen reduction reaction application.

A hydrothermal approach was adopted to synthesize tungsten oxide (WO) nanocatalysts with tailored morphology, using oxalic acid (HCO) and hydrochloric acid (HCl) as precursors. This precursor-driven method yielded two distinct WO catalysts with unique structural and functional properties, viz. rod-shaped WO-ox and nanoflower-shaped WO-h.

Identifying genetic determinants of forage sorghum [Sorghum bicolor (Moench)] adaptation through GWAS.

Background: Forage sorghum is a highly valued crop in livestock feed production due to its versatility, adaptability, high productivity, and resilience under adverse environmental conditions, making it a crucial option for sustainable forage production. This study aimed to investigate ninety-five forage sorghum genotypes and identify the marker - trait associations (MTAs) in adaptive traits, including yield and flowering through genome-wide association studies (GWAS).

Results: Using 41,854 polymorphic SNPs, a GWAS involving the GLM, MLM, and FarmCPU models was performed to analyse fourteen adaptive traits.

Real World Outcomes with Treatment Free Remission in Chronic Myeloid Leukemia-Experience from a Tertiary Care Cancer Centre.

Chronic myeloid leukaemia (CML) is caused by balanced translocation t(9::22)(q34;q11) resulting in formation of pathogenic BCR-ABL fusion gene. Tyrosine kinase inhibitors (TKI) have revolutionised the treatment of CML. Ongoing treatment with TKI leads to side effects and has financial impact.

Analysis of data of COVID lockdown period: Comorbidity and fatality rates in a few districts of Assam, India.

In many regions of the world, significant data collection, analysis, and availability on comorbidity and fatality incidents caused by COVID-19 during the lockdown period (2020-2022) is rare. This is especially true for hospitals and COVID treatment facilities in India. This lack of understanding impedes the development of appropriate treatment options, potentially resulting in inferior planning, patient recovery results, and a load on healthcare resources.

Heterojunction semiconductor nanocatalysts as cancer theranostics.

Cancer nanotechnology is a promising area of cross-disciplinary research aiming to develop facile, effective, and noninvasive strategies to improve cancer diagnosis and treatment. Catalytic therapy based on exogenous stimulus-responsive semiconductor nanomaterials has shown its potential to address the challenges under the most global medical needs. Semiconductor nanocatalytic therapy is usually triggered by the catalytic action of hot electrons and holes during local redox reactions within the tumor, which represent the response of nontoxic semiconductor nanocatalysts to pertinent internal or external stimuli.

Anaesthetic concerns in a patient with aortic aneurysm for non-cardiac surgery: A case report.

Abdominal aortic aneurysm poses a significant risk of rupture, with mortality rates of 80% to 90% if untreated. Management focuses on identifying and repairing the aneurysm before rupture, considering factors like size, type and symptoms. We report successful anaesthetic management in a case of intertrochanteric fracture of femur of an elderly patient who was to undergo elective surgery for abdominal aortic aneurysm.

Skin Carotenoids Are Related to Cognitive Abilities among Toddlers.

Background: Carotenoids are antioxidant pigments that deposit in human tissues (e.g., skin, macula, and brain) upon dietary consumption.

MRI Radiomics in Imaging of Focal Hepatic Lesions: A Narrative Review.

Magnetic resonance imaging (MRI) is generally used to identify, describe, and evaluate treatment responses for focal hepatic lesions. However, the diagnosis and differentiation of such lesions require considerable input from radiologists. In order to reduce these difficulties, radiomics is an artificial intelligence (AI)-based quantitative method that employs the extraction of image features to reliably detect and differentiate focal hepatic lesions.

Comparative Study of Levels of Serum Bilirubin, Serum Transaminase, Serum Alkaline Phosphatase, and Prothrombin Time After Laparoscopic Cholecystectomy and Open Cholecystectomy.

Laparoscopic cholecystectomy (LC) is universally accepted as the gold standard treatment for symptomatic gallstones. However, it has some drawbacks. Some of the major drawbacks of LC include increased bile duct injuries and longer operation time.

Integrated photonic encoder for low power and high-speed image processing.

Modern lens designs are capable of resolving greater than 10 gigapixels, while advances in camera frame-rate and hyperspectral imaging have made data acquisition rates of Terapixel/second a real possibility. The main bottlenecks preventing such high data-rate systems are power consumption and data storage. In this work, we show that analog photonic encoders could address this challenge, enabling high-speed image compression using orders-of-magnitude lower power than digital electronics.

Tuning the Thermochemistry and Reactivity of a Series of Cu-Based 4H/4e Electron-Coupled-Proton Buffers.

Electron-coupled-proton buffers (ECPBs) store and deliver protons and electrons in a reversible fashion. We have recently reported an ECPB based on Cu and a redox-active ligand that promoted 4H/4e reversible transformations ( , 144, 16905). Herein, we report a series of Cu-based ECPBs in which the ability of these to accept and/or donate H equivalents can be tuned via ligand modification.

Genetic gains in forage sorghum for adaptive traits for non - conventional area through multi-trait-based stability selection methods.

Introduction: In the Asian tropics, unpredictable weather increases the risk of abiotic stresses in sorghum areas, making it harder to meet predicted demand. Genotype-by environment interaction (GEI) and the lack of an effective multi-trait-based selection approach make it challenging to breed climateresilient forage sorghum that adapts to nonconventional areas.

Methods: The present investigation carried out to estimate genetic parameters, inter trait associations, genetic gain under selection (SGs) of 95 diverse forage sorghum genotypes.

Giant Thermoelectric Response of Confined Electrolytes with Thermally Activated Charge Carrier Generation.

The thermoelectric response of thermally activated electrolytes (TAEs) in a slit channel is studied theoretically and by numerical simulations. The term TAE refers to electrolytes whose charge carrier concentration is a function of temperature, as recently suggested for ionic liquids and highly concentrated aqueous electrolyte solutions. Two competing mechanisms driving charge transport by temperature gradients are identified.

Is developmental plasticity triggered by DNA methylation changes in the invasive cane toad ()?

Many organisms can adjust their development according to environmental conditions, including the presence of conspecifics. Although this developmental plasticity is common in amphibians, its underlying molecular mechanisms remain largely unknown. Exposure during development to either 'cannibal cues' from older conspecifics, or 'alarm cues' from injured conspecifics, causes reduced growth and survival in cane toad () tadpoles.

Grain iron and zinc content is independent of anthocyanin accumulation in pigmented rice genotypes of Northeast region of India.

The traditional rice genotypes of Assam are considered to have biological value due to the presence of several bioactive compounds like flavonoids, polyphenols, and anthocyanins, which have antioxidant, anti-cancer, anti-diabetic, and anti-aging properties. The pigmented genotypes are considered to have high iron (Fe) content. However, the effect of Fe and Zinc (Zn) accumulation on anthocyanin content is yet to be studied in pigmented rice of Assam.

A Comparative Study Evaluating the Quality of Life and Survival Outcomes in Patients Receiving Chemotherapy Versus Oral Tyrosine Kinase Inhibitor in the Third Line and Beyond Setting for Advanced NSCLC.

Introduction: The outcomes in advanced NSCLC have improved owing to the availability of more effective systemic and improved supportive care. This has increased the number of patients who seek treatment in the third line and beyond setting. We conducted this study to compare the quality of life (QoL), toxicity, and outcomes in patients receiving chemotherapy and EGFR tyrosine kinase inhibitors (TKIs) in this setting.

Drug resistance profile in postbiliary and gastrointestinal surgical-site infection cases from a tertiary care hospital.

In the developing world, surgical-site infection (SSI)-associated pathogens are becoming more drug resistant implicating higher morbidity and management cost. Here, we tried to analyze the drug resistance pattern in our SSI-related isolates. Over 2 years, 191 clinically diagnosed SSIs (postbiliary tract and postgastrointestinal surgery) were included, and wound swabs were processed by conventional aerobic and anaerobic culture.

Immunoassay testing for barbiturates using alternative matrices in postmortem tissues from cats and dogs.

The barbiturate drug pentobarbital is commonly used by veterinarians for the euthanasia of domestic animals. During the veterinary forensic autopsy, it is sometimes necessary to determine whether the animal was chemically euthanized with pentobarbital. The use of a human immunochromatographic test for barbiturate screening utilizing dog or cat urine has been previously validated; however, the use of alternative matrices for this purpose is yet to be explored when urine is not available.

Memory Abilities Are Selectively Related to Food Label and Numeracy Nutrition Skills.

Objective: We investigated the relationship between nutrition literacy, diet quality, carotenoid status, and cognition.

Methods: Adults aged 37.5 ± 17.

Improved epitaxial growth and multiferroic properties of BiFeMnO using CeO re-seeding layers.

In ferroelectric and multiferroic-based devices, it is often necessary to grow thicker films for enhanced properties. For certain phases that rely on substrate strain for growth, such thicker film growths beyond the typical thin film regime could be challenging. As an example, the BiFeMnO (BFMO) Aurivillius supercell (SC) phase possesses highly desirable multiferroic (, ferromagnetic and ferroelectric) properties and a unique layered structure but relies heavily on substrate strain.

Hemolytic Anemia in the Setting of Atypical Pneumonia: A Case of Cold Agglutinin Disease.

Cold agglutinin hemolytic anemia (cAHA) is a rare autoimmune disorder characterized by the production of cold agglutinins. We present a case of secondary cAHA in a 23-year-old female with severe anemia and unexplained hemolysis. The patient exhibited findings indicative of hemolysis and a positive direct antiglobulin test (DAT) with complement alone.