Analyzing the Impact of Various Jump Load Intensities on Countermovement Jump Metrics: A Comparison of Average, Peak, and Peak-to-Average Ratios in Force-Based Metrics.

The purpose was to create a systematic approach for analyzing data to improve predictive models for fatigue and neuromuscular performance in volleyball, with potential applications in other sports. The study aimed to assess whether average, peak, or peak-to-average ratios of countermovement jump (CMJ) force plate metrics exhibit stronger correlations and determine which metric most effectively predicts performance. Data were obtained from nine division I female volleyball athletes over a season, recording daily jump loads (total jumps, jump counts >38.

Dose-Response Effects of Exercise and Testosterone Replacement Therapy on Body Composition, Lean Mass, and Heart Rate Responses: A Case Report Using Wearable Technology.

The case report explores the effects of testosterone replacement therapy (TRT) on body composition, lean muscle mass, and fat mass, based on the dosage of TRT and exercise intensity in a 40-year-old male. The purpose of this case study was to evaluate the dose-response relationship of TRT and exercise on muscle hypertrophy and fat loss over an eight-month period, using a validated wrist-worn wearable fitness tracker to measure daily physical activity and heart rate (HR)-based exercise intensity. The patient, a trained male with 25 years of consistent exercise experience, reported notable declines in strength and increases in body fat despite maintaining a regular workout routine.

Positional Differences in Jump Loads and Force and Velocity Metrics Throughout a 16-Week Division I Volleyball Season.

The study quantified total and high-intensity jump counts and assessed neuromuscular performance through countermovement jump (CMJ) force and velocity metrics by position. Twelve Division I female athletes (19.6 ± 1.

Countermovement Jumps and Acute to Chronic Workload Ratios in Low, Moderate, and High Jump Load Groups Throughout a Division I Volleyball Season.

Sanders, GJ, Skodinski, S, Cabarkapa, DV, Howard, M, Cabarkapa, D, Kollock, RO, and Peacock, CA. Countermovement jumps and acute to chronic workload ratios in low, moderate, and high jump load groups throughout a Division I volleyball season. J Strength Cond Res XX(X): 000-000, 2024-The purpose of the study was to evaluate the effects of low, moderate, and high jump loads on the acute to chronic workload ratio (ACWR) and neuromuscular fatigue throughout a Division I volleyball season.

Relationship between self-reported concussion history, cognition, and mood among former collegiate athletes.

: This study explored the relationship between concussion history and cognition/mood in former collegiate athletes in middle-to-later adulthood. : 407 former collegiate athletes aged 50+ ( = 61.4; 62.

Preliminary clinical performance of a Cas13a-based lateral flow assay for detecting in urine specimens.

Nucleic acid amplification testing (NAAT) for is unavailable in resource-limited settings. We previously developed a CRISPR-based lateral flow assay for detecting . We aimed to pair that assay with point-of-care DNA extraction, assess performance in clinical urine specimens, and optimize assay kinetics.

Repetitive head-injury exposure and later-in-life cognitive and emotional outcomes among former collegiate football players: a CLEAATS investigation.

This study measured the relationship between head-injury exposure and later-in-life cognitive and emotional symptoms in aging collegiate football players who participated in the College Level Aging Athlete Study. Linear regressions examined the relationship between various head-injury exposure variables (head-injury exposure estimate [HIEE], number of diagnosed concussions, and symptomatic hits to the head) and subjective cognitive function, objective cognitive function, and emotional/mood symptoms. Additional regressions evaluated the impact of emotional symptoms on subjective cognitive decline and objective cognitive function.

Host Jump of an Exotic Fish Rhabdovirus into a New Class of Animals Poses a Disease Threat to Amphibians.

Spring viremia of carp virus (SVCV) is a rhabdovirus that primarily infects cyprinid finfishes and causes a disease notifiable to the World Organization for Animal Health. Amphibians, which are sympatric with cyprinids in freshwater ecosystems, are considered non-permissive hosts of rhabdoviruses. The potential host range expansion of SVCV in an atypical host species was evaluated by testing the susceptibility of amphibians native to the Pacific Northwest.

Association of Cardiologist Clinic Visits with Cardiovascular Primary Prevention Outcomes Among People with HIV from Underrepresented Racial and Ethnic Groups in the Southern United States.

Background: People with HIV (PWH) are at elevated risk for atherosclerotic cardiovascular disease (ASCVD). Underrepresented racial and ethnic groups (UREGs) with HIV in the southern U.S.

Immunoglobulin E-mediated food allergy diagnosis and differential diagnosis.

Food allergies consist of aberrant immunologic, typically immunoglobulin E mediated, reactions that involve food proteins. A clinical history with regard to the suspected food, temporal associations, the duration of symptoms, characteristic symptom complex, and reproducibility in some cases is the key to making an accurate diagnosis. The differential diagnosis includes, for example, other immunologic adverse food reactions, nonimmunologic adverse food reactions, and reactions that involve nonfood items.

Conformations of influenza A M2 protein in DOPC/DOPS and E. coli native lipids and proteins.

We compared the conformations of the transmembrane domain (TMD) of influenza A M2 (IM2) protein reconstituted in 1,2-dioleoyl-sn-glycero-3-phosphocholine/1,2-dioleoyl-sn-glycero-3-phospho-L-serine (DOPC/DOPS) bilayers to those in isolated Escherichia coli (E. coli) membranes, having preserved its native proteins and lipids. IM2 is a single-pass transmembrane protein known to assemble into a homo-tetrameric proton channel.

Relationship between Simulated Fire Suppression Activities and Acute Cardiac and Respiratory Events in Firefighters.

Cardiac deaths account for the largest share of on-duty firefighter deaths. To help ensure duty fitness and minimize injury risk, many fire departments require the passing of an annual physical ability test, consisting of a battery of simulated fire suppression activities (sFSAs). The purpose of the study was to determine the relationship of sFSA performance to acute cardiac and respiratory events (ACREs) and the effect that estimated VOmax has on sFSA performance.

Process evaluation of implementation of the early stages of a whole systems approach to obesity in a small Island.

Background: The small Atlantic island of St Helena is a United Kingdom Overseas Territory (UKOT) with a high prevalence of childhood obesity (over a quarter of 4-5 and 10-11 year olds) and, anecdotally, adulthood obesity and its associated health detriments. St Helena have taken a whole systems approach to obesity (WSAO) to address the issue. A WSAO recognises the factors that impact obesity as a complex system and requires a 'health in all policies' approach.

Prediction of pediatric peanut oral food challenge outcomes using machine learning.

Background: Clinical testing, including food-specific skin and serum IgE level tests, provides limited accuracy to predict food allergy. Confirmatory oral food challenges (OFCs) are often required, but the associated risks, cost, and logistic difficulties comprise a barrier to proper diagnosis.

Objective: We sought to utilize advanced machine learning methodologies to integrate clinical variables associated with peanut allergy to create a predictive model for OFCs to improve predictive performance over that of purely statistical methods.

Racial and Socioeconomic Disparities Exist in Patients Pursuing Peanut Oral Immunotherapy.

Background: Oral immunotherapy (OIT) is a promising treatment for food allergy. Prior studies demonstrate significant differences among food-allergic individuals across race, ethnicity, and socioeconomic groups. Disparities in OIT have not been evaluated.

Clinical Performance of Cas13a-based Point-of-Care Lateral Flow Assay for Detecting .

Background: Diagnosis of is dependent on nucleic acid amplification testing (NAAT), which is not available in resource-limited settings where the prevalence of infection is highest. Recent advances in molecular diagnostics leveraging the high specificity of CRISPR enzymes can permit field-deployable, point-of-care lateral flow assays. We previously reported on the development and performance of a lateral flow assay for detecting .

Relationship between sex, body size, and cardiac resynchronization therapy benefit: A patient-level meta-analysis of randomized controlled trials.

Background: Women might benefit more than men from cardiac resynchronization therapy (CRT) and do so at shorter QRS durations.

Objective: This meta-analysis was performed to determine whether sex-based differences in CRT effects are better accounted for by height, body surface area (BSA), or left ventricular end-diastolic dimension (LVEDD).

Methods: We analyzed patient-level data from CRT trials (MIRACLE, MIRACLE ICD, MIRACLE ICD II, REVERSE, RAFT, COMPANION, and MADIT-CRT) using bayesian hierarchical Weibull regression models.

A comparative study of influenza A M2 protein conformations in DOPC/DOPS liposomes and in native membranes.

We compared the conformations of the transmembrane domain (TMD) of influenza A M2 (IAM2) protein reconstituted at pH 7.4 in DOPC/DOPS bilayers to those in isolated membranes, having preserved its native proteins and lipids. IAM2 is a single-pass transmembrane protein known to assemble into homo-tetrameric proton channel.

The Effect of Daily Heart Rate Workloads on Preseason, Midseason, and Postseason Oxygen Consumption in Division I Basketball.

Howard, M, Sanders, GJ, Kollock, RO, Peacock, CA, and Freire, R. The effect of daily heart rate workloads on preseason, midseason, and postseason oxygen consumption in Division I basketball. J Strength Cond Res 38(4): 704-708, 2024-Basketball is a dynamic sport, requiring athletes to elicit a high-level of physical, tactical, technical, and psychological attributes and athletes must possess a robustly trained aerobic energy system.

Benefit of cardiac resynchronization therapy among older patients: A patient-level meta-analysis.

Background: Cardiac resynchronization therapy (CRT) reduces heart failure hospitalizations (HFH) and mortality for guideline-indicated patients with heart failure (HF). Most patients with HF are aged ≥70 years but such patients are often under-represented in randomized trials.

Methods: Patient-level data were combined from 8 randomized trials published 2002-2013 comparing CRT to no CRT (n = 6,369).

Three-tiered approach for standard information requirements for polymers requiring registration under REACH.

Polymers are a very large class of chemicals comprising often complex molecules with multiple functions used in everyday products. The EU Commission is seeking to develop environmental and human health standard information requirements (SIRs) for man-made polymers requiring registration (PRR) under a revised Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) Regulation. Conventional risk assessment approaches currently used for small molecules may not apply to most polymers.

Comorbidities and clinical response to cardiac resynchronization therapy: Patient-level meta-analysis from eight clinical trials.

Aims: Patients with heart failure usually have several other medical conditions that might alter the effects of interventions. We investigated whether the burden of comorbidity modified the clinical response to cardiac resynchronization therapy (CRT).

Methods And Results: Original patient-level data from eight randomized trials exploring the effects of CRT versus no CRT were pooled (BLOCK-HF, MIRACLE, MIRACLE-ICD, MIRACLE-ICD II, RAFT, COMPANION, MADIT-CRT and REVERSE).