Publications by authors named "SALOMON L"

Background: Most young adults with perinatal HIV (PHIV) transition from pediatric or adolescent to adult clinical care. Although guidelines to increase transition success have been recommended, we know little about uptake of these guidelines, particularly by adult care clinics.

Methods: We administered web-based surveys to adult care providers of young adults with PHIV in Massachusetts to evaluate transition preparation and post-transition evaluation practices.

View Article and Find Full Text PDF

Background: Achondroplasia, due to a specific pathogenic variant in FGFR3, is the most common viable skeletal dysplasia and the diagnosis is mostly done in the prenatal period. Since 2021, the use of Vosoritide, a specific treatment for achondroplasia, validated in phase 3 placebo-controlled trials, has been recommended to significantly increase the height of children and infants. In the light of these new therapeutic prospects, a complete understanding of the pathophysiology of skeletal damages occurring from foetal life is required.

View Article and Find Full Text PDF

Background: Minor Ophthalmic Procedures (MOP), especially cataract or glaucoma surgery, are considered low risk. However, in France, anesthesia must be monitored continuously and carried out by an anesthetist or a nurse anesthetist (NA). The aim was to assess whether an externalized monitored anesthesia care (MAC) would be non-inferior to an individual MAC inside the OR regarding the incidence of severe hypertension, bradycardia, hypoxemia, and surgeon satisfaction.

View Article and Find Full Text PDF

Objective: To determine the prevalence of genetic and endocrine abnormalities and to assess fetal, neonatal and surgical outcomes in cases of hypospadias associated with fetal growth restriction.

Method: A multicentric retrospective study was conducted across five prenatal diagnosis centers in Paris. The cohort encompassed all fetuses diagnosed with the combination of fetal growth restriction < 10th percentile (FGR) and hypospadias from 2013 to 2021.

View Article and Find Full Text PDF

Objective: To identify prenatal predictors of poor perinatal outcome in fetuses with isolated sacrococcygeal teratoma (SCT).

Methods: This was a retrospective study of fetuses with isolated (non-syndromic) SCT managed at one of five pediatric surgery and/or fetal medicine centers between January 2007 and December 2017. The primary outcome was the occurrence of poor perinatal outcome, defined as prenatal death (including termination), or neonatal death or severe compromise (hemorrhagic shock).

View Article and Find Full Text PDF
Article Synopsis
  • Preeclampsia is a pregnancy-related condition linked to placental problems, studied in mice using the STOX1A model which simulates symptoms like high blood pressure and protein in urine.
  • The study compared placental perfusion in two groups of pregnant mice (TgSTOX13 vs. wild-type) using advanced imaging techniques to measure blood flow and other health indicators.
  • Results showed that the TgSTOX13 group had significantly higher blood pressure, protein levels in urine, and lower fetal weights, along with a 30% reduction in placental blood flow, reflecting similar issues seen in human preeclampsia cases.
View Article and Find Full Text PDF

Objective: To assess the frequency of fetal therapy for fetuses with congenital pulmonary malformations (CPMs) and to investigate their short-term outcomes.

Method: The study population included 435 singleton fetuses diagnosed with CPMs from a national population-based cohort study in France in 2015-2018. Information was obtained from medical records on CPM volume ratio (CVR), signs of compression, fetal therapy and perinatal outcomes.

View Article and Find Full Text PDF

Objectives: Accurate assessment of gestational age (GA) is important at both individual and population levels. The most accurate way to estimate GA in women who book late in pregnancy is unknown. The aim of this study was to externally validate the accuracy of equations for GA estimation in late pregnancy and to identify the best equation for estimating GA in women who do not receive an ultrasound scan until the second or third trimester.

View Article and Find Full Text PDF

Introduction: Over 265 000 women are living with HIV in the USA, but limited research has investigated the physical, mental and behavioural health outcomes among women living with HIV of reproductive age. Health status during the reproductive years before, during and after pregnancy affects pregnancy outcomes and long-term health. Understanding health outcomes among women living with HIV of reproductive age is of substantial public health importance, regardless of whether they experience pregnancy.

View Article and Find Full Text PDF

Olfaction is influenced by contextual factors, past experiences, and the animal's internal state. Whether this information is integrated at the initial stages of cortical odour processing is not known, nor how these signals may influence odour encoding. Here we revealed multiple and diverse non-olfactory responses in the primary olfactory (piriform) cortex (PCx), which dynamically enhance PCx odour discrimination according to behavioural demands.

View Article and Find Full Text PDF

Importance: Pregnancy represents a window of opportunity for vaccination due to established maternal and fetal benefits of vaccination. Little is known about receipt of routinely recommended vaccines in pregnancy, specifically tetanus, diphtheria, plus acellular pertussis (Tdap) and influenza, among pregnant people living with HIV (PLHIV).

Objective: To estimate prevalence of vaccination receipt among pregnant people with HIV (PLHIV) and identify demographic and clinical characteristics associated with vaccination.

View Article and Find Full Text PDF

Objective: To report our experience of fetal aortic valvuloplasty (FAV) for critical aortic stenosis (AS), with a focus on the postnatal evolution of the patients.

Methods: This was a retrospective study including all fetuses with critical AS which underwent FAV in a single center between January 2011 and June 2022. FAV was performed under ultrasound guidance.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the effectiveness of cell-free DNA (cfDNA) testing for detecting fetal aneuploidies in women with triplet pregnancies, as current data is limited compared to singleton pregnancies.
  • The research involved a retrospective analysis of 255 women who underwent cfDNA testing between 2017 and 2020, focusing primarily on trisomy 21 (T21) and secondarily on trisomy 18 (T18) and trisomy 13 (T13).
  • Results indicated that cfDNA testing can serve as a primary screening tool for major fetal aneuploidies in triplet pregnancies, highlighting the importance of informed patient consent before proceeding with the test.
View Article and Find Full Text PDF
Article Synopsis
  • In early 2023, a study demonstrated that vaccinating pregnant women effectively reduces the chances of severe COVID-19 complications and maternal health issues.
  • The INTERCOVID-2022 study, conducted across 40 hospitals in 18 countries, analyzed how COVID-19 during pregnancy affects newborns and the benefits of maternal vaccination during the Omicron variant period.
  • Results showed that newborns from mothers who received a booster vaccine had significantly lower risks of contracting COVID-19 and experiencing preterm birth compared to those from unvaccinated mothers.
View Article and Find Full Text PDF

Objectives: T2*-weighted magnetic resonance imaging (MRI) sequences have been identified as non-invasive tools with which to study placental oxygenation in vivo. This study aimed to use these to investigate both static and dynamic responses to hyperoxia of the normal placenta across gestation.

Methods: We conducted a single-center prospective study including 52 uncomplicated pregnancies.

View Article and Find Full Text PDF

In order to cope with the challenges of living in dynamic environments, animals rapidly adjust their behaviors in coordination with different physiological responses. Here, we studied whether threatening visual stimuli evoke different heart rate patterns in arthropods and whether these patterns are related with defensive behaviors. We identified two sequential phases of crab's cardiac response that occur with a similar timescale to that of the motor arrest and later escape response.

View Article and Find Full Text PDF
Article Synopsis
  • This study evaluates the effectiveness of cytogenetic testing through amniocentesis in fetuses diagnosed with isolated bilateral talipes equinovarus after an ultrasound.
  • It involved a retrospective analysis of 214 cases, where various prenatal data and outcomes were tracked from five fetal medicine centers between 2012 and 2021.
  • The results indicated that the majority of cases had normal genetic outcomes, with a high live birth rate, but three medical terminations occurred due to significant genetic disorders detected through testing.
View Article and Find Full Text PDF

Introduction: Decisions to disclose HIV serostatus may be complicated by internalised HIV stigma. We evaluated the association of internalised HIV stigma in biological mothers living with HIV with disclosure of their serostatus to their children perinatally HIV-exposed but uninfected (CHEU).

Methods: Mothers and their CHEU were enrolled in the United States (U.

View Article and Find Full Text PDF