Publications by authors named "S van den Ameele"

The prevalence of young people with at least one parent from a migrant background is increasing. These families deal with the complexities of navigating between cultures. This challenges patients and mental health workers in their aim to find a culturally sensitive approach.

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The COVID-19 pandemic had a major worldwide impact resulting in more than 7 million deaths due to COVID-19. Mental health issues, including anxiety, depression, and post-traumatic stress disorder (PTSD) have been observed in COVID-19 survivors worldwide. This study aimed to investigate the psychological impact of COVID-19 survivors three months after discharge from hospital and examine associated risk factors.

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Article Synopsis
  • The immune system plays a crucial role in major depressive disorder (MDD), with about 30% of depressed patients exhibiting inflammation and atypical symptoms, leading to a poorer response to standard antidepressants.
  • The INSTA-MD trial is a 12-week, double-blind study assessing the effectiveness of minocycline or celecoxib as adjunct treatments for patients with MDD who have not responded to previous antidepressant trials.
  • The trial will stratify participants based on their inflammation levels (high vs. low hsCRP) and aims to determine if this stratification can help predict treatment response and improve outcomes with these immune-targeted therapies.
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Background: Despite a high prevalence of mental disorders among asylum seekers, many barriers to mental healthcare exist. Cultural and contextual factors strongly influence the experience and expression of psychological distress, putting asylum seekers at greater risk of misdiagnosis and inappropriate treatment. The Cultural Formulation Interview (CFI) is a useful tool to map out cultural and contextual factors of mental disorders; however, to the best of our knowledge, it has not yet been investigated in asylum seekers specifically.

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An increase of psychopathology such as post-traumatic stress disorder (PTSD) is described in patients affected with COVID-19 that stayed at an intensive care unit (ICU). However, data on follow-up and on impact of contextual factors are limited. In a single-center, observational study, PTSD symptomatology was prevalent among 38% of participants (n=8), persisting in clinical PTSD in 2 participants after one year.

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