The efficacy of toltrazuril for prevention of oriental theileriosis (Theileria orientalis Ikeda genotype) in Friesian calves.

The aim of this non-blinded, randomised, controlled study was to determine the efficacy of toltrazuril for the prevention of oriental theileriosis in calves. Thirty calves were infected with Theileria orientalis Ikeda genotype through the application and retention of infected female bush ticks (Haemaphysalis longicornis). 15 Group 1 calves were treated with a single, oral dose of toltrazuril at the dose registered in Australia for coccidiosis (15 mg/kg), concurrently with tick infection, and 15 Group 2 (control group) calves were untreated.

Eight-month repellency and efficacy of an imidacloprid/flumethrin (Seresto ) collar against the eastern paralysis tick (Ixodes holocyclus) on cats.

Objective: The objective of this study was to determine the repellency and efficacy of a 10% imidacloprid/4.5% flumethrin (Seresto , Elanco) collar over an 8-month period against the eastern paralysis tick (Ixodes holocyclus) on cats.

Methods: Two non-blinded, open gender, randomised, placebo-controlled pen studies were conducted, with 26 cats enrolled in each study.

Merozoites of Theileria orientalis buffeli reduce the parasitaemia of T. orientalis ikeda following tick challenge.

Theileria orientalis is a tick-borne protozoal parasite causing anaemia and death in susceptible cattle. This investigation aimed to confirm whether immunisation with the "benign" buffeli genotype of T. orientalis could reduce the parasitaemia of the virulent ikeda genotype.

Cefpirome Treatment Results in Limited Selection of Stable Derepressed Mutants in the Intestinal Flora of Rats Treated for an Experimental Pulmonary Infection.

Fourth-generation cephalosporins have been developed to improve their potency, that is, low minimal inhibitory concentrations (MICs) and to prevent resistance selection of derepressed AmpC-producing mutants in comparison to third-generation cephalosporins as ceftazidime. We investigated the role of the administered cefpirome dose on the efficacy of treatment of a lung infection as well as in the selection of resistant isolates in the intestines of rats treated for a lung infection. Rats with lung infection received therapy with cefpirome doses of 0.

PME and Other ESBL-Positive Multiresistant Pseudomonas aeruginosa Isolated from Hospitalized Patients in the Region of Kurdistan, Iraq.

Nosocomial infections occur worldwide and also in the Kurdistan region. Frequently patients colonized with multiresistant Pseudomonas aeruginosa isolates are encountered in many hospitals. As information is lacking with respect to the mechanisms of resistance responsible for the multiresistant character of the P.