Publications by authors named "S de las Heras"
Background: The detection of genetic sequences represents the gold standard procedure for species discrimination, genetic characterisation of tumours, and identification of pathogens. The development of new molecular detection methods, accessible and cost effective, is of great relevance. Biosensors based on plasmonic nanoparticles, such as gold nanoparticles (AuNPs), provide a powerful and versatile platform for highly sensitive, economic, user-friendly and label-free sensing.
View Article and Find Full Text PDFRecent studies have demonstrated the association between constitutional ring chromosome 21 (r(21)c) and the development of B-cell acute lymphoblastic leukemia (B-ALL) with intrachromosomal amplification of chromosome 21 (iAMP21). iAMP21 acts as a driver which is often accompanied by secondary alterations that influence disease progression. Here, we report an atypical case of iAMP21 B-ALL with a unique molecular profile in the context of r(21)c.
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- The study focuses on the giant red shrimp, a valuable marine species, emphasizing the importance of understanding its biology for effective conservation and management strategies.
- Researchers developed and characterized new microsatellite markers through next-generation sequencing, identifying 19 polymorphic loci after testing 58 candidates across a global panel of shrimp individuals.
- The identified loci will aid in parentage analysis and understanding the population structure and connectivity of the giant red shrimp across different geographical areas, particularly between exploited and unexploited environments.
The aim of the present work was to gain insight into the metabolism of pigs derived from assisted reproductive technologies during their adulthood. Approximately 4h after feeding, a blood sample was taken from 3.5 year old sows born by artificial insemination (AI group, n = 7) and transfer of in vitro produced embryos (IVP group, n = 11) to determine the physiological concentrations of the main biomarkers of carbohydrates (glucose and lactate), proteins (albumin, creatinine and urea) and lipids (cholesterol and triglycerides).
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- Chagas disease (CD) is gaining attention in the US, originally a Latin American issue, due to increased human migration and the presence of disease vectors and hosts within the country.
- The research project reviewed 34 studies on the genetic diversity of the disease in triatomine insects and mammalian hosts across 18 US states, primarily focused on Texas, Louisiana, and New Mexico.
- TcI and TcIV were the main genetic types found, with TcI being the most prevalent, highlighting the need for ongoing monitoring and management of Chagas disease as its distribution may change over time.