Publications by authors named "S de Rooij"
Background: Trauma-focused psychotherapy is treatment of choice for post-traumatic stress disorder (PTSD). However, about half of patients do not respond. Recently, there is increased interest in brain criticality, which assesses the phase transition between order and disorder in brain activity.
View Article and Find Full Text PDFObjective: Evidence suggests that children with psychosocial problems face a higher risk of cardiometabolic diseases in adulthood. However, this may already be evident prior to adulthood. In this study, the associations between psychosocial problems at preschool age and cardiometabolic outcomes 6 years later were investigated.
View Article and Find Full Text PDFSocial Buffering of PTSD: Longitudinal Effects and Neural Mediators.
Biol Psychiatry Cogn Neurosci Neuroimaging
November 2024
Article Synopsis
- This study investigates how early social support after trauma affects PTSD symptoms over time and explores specific brain regions involved in this process, such as the amygdala and ventromedial prefrontal cortex.
- Using data from 315 participants in the AURORA study, researchers measured PTSD symptoms and perceived emotional support at multiple time points, while also conducting neuroimaging two weeks post-trauma.
- The results show that early emotional support is linked to changes in white matter connectivity between key brain areas, but it also highlighted unexpected increased threat reactivity in the default mode network, suggesting complex neural pathways in response to social threats.
Article Synopsis
- Maternal stress during the postpartum period affects the nutrient composition and microbiome of human milk (HM), potentially impacting early development and mental health outcomes for infants.
- A study involving high-stress (HS) and control groups analyzed HM microbiome changes, revealing distinct differences in bacterial composition, particularly showing HS mothers had altered levels of certain bacteria like reduced Streptococcus and increased Staphylococcus.
- The findings indicate a strong correlation between maternal stress and changes in the HM microbiome, suggesting these alterations could influence infant gut colonization and overall health, necessitating further research on their implications.