Publications by authors named "S al-Khalifa"
Article Synopsis
- This study assessed the risks related to maternal obesity (BMI ≥30) during pregnancy and the postpartum period among 2972 pregnant women at a hospital in Bahrain.
- Key findings indicate that higher BMI is linked to increased age, high parity, a history of miscarriages, and a greater risk of developing conditions like hypertension and antepartum hemorrhage.
- Despite these risks, high BMI patients did not show an increased likelihood of gestational diabetes, induction of labor, or cesarean births, but they faced longer hospital stays after delivery.
Quaternary ammonium compounds (QACs) are ubiquitous antiseptics whose chemical stability is both an aid to prolonged antibacterial activity and a liability to the environment. Soft antimicrobials, such as QACs designed to decompose in relatively short times, show the promise to kill bacteria effectively but not leave a lasting footprint. We have designed and prepared 40 soft QAC compounds based on both ester and amide linkages, in a systematic study of mono-, bis-, and tris-cationic QAC species.
View Article and Find Full Text PDFA series of 18 bis- and tris-pyridinium amphiphiles were prepared and tested for both antimicrobial activity and lytic capability, in comparison with the commercially available pyridinium antiseptic cetylpyridinium chloride (CPC). Assessments were made against Gram-positive and Gram-negative bacteria, including two methicillin-resistant Staphylococcus aureus (MRSA) strains. While 2Pyr-11,11 was identified as one of the most potent antimicrobial quaternary ammonium compounds (QACs) reported to date, boasting nanomolar inhibition against five of six bacteria tested, no significant improvement in bioactivity of tris-pyridinium amphiphiles over their bis-pyridinium counterparts was observed.
View Article and Find Full Text PDFChromobacterium violaceum is a Gram-negative organism found in water and soil. C. violaceum is not usually pathogenic in humans; only approximately 150 human cases have been reported worldwide.
View Article and Find Full Text PDFIntroduction: The assessment and maintenance of competence for pediatricians has recently received increased attention. The aim of the present study was to investigate further the use of multisource feedback for assessing pediatricians in practice.
Methods: A systematic literature review was conducted using the electronic databases EMBASE, PsycINFO, MEDLINE, PUBMED, and CINAHL for English-language articles.