First detection of Chlamydia trachomatis LGV biovar in the Czech Republic, 2010-2011.

We present four cases of proctitis in HIV-infected men having sex with men (MSM) living in the Czech Republic. The causative agent in all cases was the lymphogranuloma venereum (LGV) biovar of Chlamydia trachomatis. The spread of proctitis caused by C.

Genetic variability of cytomegalovirus glycoprotein O in hematopoietic stem cell transplant recipients.

Unlabelled: Genetic variation of cytomegalovirus (CMV) strains can correlate with their pathogenicity for immunocompromised patients. Glycoprotein O (gO), together with glycoprotein L and glycoprotein H, mediate the fusion of the viral envelope with the cell membrane and promotes virus penetration, envelopment, and release. The variability of gO might play a role in CMV cell tropism.

[Prevalence of glycoprotein B (gB) genotypes in the patients with high risk of symptomatic cytomegalovirus infection].

Objectives: Based on genetic variability of the dominant envelope glycoprotein (gB), human cytomegalovirus is classified into four major genotypes. The aims were to determine the prevalence of particular gB genotypes in Czech CMV-infected patients and to compare three groups of the patients with high risk of symptomatic CMV infection, i.e.

[Genotyping of viral glycoprotein B (gB) in hematopoietic stem cell transplant recipients with active cytomegalovirus infection: analysis of the impact of gB genotypes on the patients' outcome].

Aim Of The Study: Genetic variation of CMV strains may correlate with their pathogenicity for immunocompromised patients. On the basis of sequence variation in the UL55 gene encoding the most abundant viral envelope glycoprotein gB, CMV can be classified into four major gB genotypes. The aim of the study was the analysis of the distribution of gB genotypes in a cohort of haematopoietic stem cell transplant (HSCT) recipients and of the correlation of genetic polymorphisms with clinical outcomes and manifestation of CMV infection.