Publications by authors named "S Zibaee"
Gastric cancer (GC) remains one of the top causes of cancer-related mortality around the world. The pathogenesis of GC is attributed to lifestyle, family history, genetic mutations, epigenetic alterations, as well as infectious agents such as Epstein-Barr Virus (EBV). EBV, a ubiquitous human gamma herpes virus, with latent asymptomatic infection in more than 95% of the world's population, is able to infect through the oral epithelium.
View Article and Find Full Text PDFBackground: Infectious bronchitis virus (IBV), Newcastle disease virus (NDV), and avian influenza virus (AIV) H9N2 are major viral pathogens in broiler respiratory disease.
Aims: Following a respiratory disease outbreak and economic losses in eastern Iran 2020-2021, we investigated the role of major viral pathogens and the implemented vaccination programs.
Methods: Thirty-six respiratory disease affected broiler flocks in South Khorasan province were sampled, molecularly tested, and coinfections were investigated.
A highly sensitive colorimetric method (glycan-based nano(e)zyme) was developed for sensitive and rapid detection of the SARS-CoV-2 virus based on N-acetyl neuraminic acid (sialic acid)-functionalized gold nanoparticles (SA-Au NZs). A number of techniques were used to characterize the prepared nanomaterials including XRD, FT-IR, UV-vis, DLS, and TEM. DLS analysis indicates an average hydrodynamic size of 34 nm, whereas TEM analysis indicates an average particle size of 15.
View Article and Find Full Text PDFBackground And Objectives: Among the various factors involved in the development of gastric cancer (GC), infectious agents are one of the most important causative inducers. This study aimed to investigate the possible role of EBV gene expression on SHP1 methylation in co-infection with in patients with GC.
Materials And Methods: Formalin-fixed paraffin-embedded samples were obtained from 150 patients with gastrointestinal disorders.
Article Synopsis
- The study investigated the EPIYA motifs of the A gene in gastric disorder patients from different regions in Iran, aiming to link these patterns to clinical outcomes.
- The research included 150 patients and found a prevalence of A gene positivity of 66.3% in eastern Iran (Mashad) and 50.6% in central Iran (Isfahan) with various EPIYA motifs identified.
- A novel EPIYA C sequence was associated with gastric cancer, suggesting a significant link between specific EPIYA motifs and the disease, marking the study as the first of its kind in these regions of Iran.