Publications by authors named "S Zengin Karahan"
Total Neoadjuvant Therapy (TNT) is a promising strategy for treating locally advanced rectal cancer (LARC) and has started to replace the traditional neoadjuvant chemoradiotherapy (CRT). This review combines findings from pivotal studies that helped TNT to integrate into clinical practice. It emphasizes the efficacy of TNT in improving the disease-free and metastasis-free survival, pathologic complete response and, according to recent studies, a potential improvement in overall survival when compared to standard CRT.
View Article and Find Full Text PDFA potential antifungal bioproduct for Microsporum canis: Bee venom.
Onderstepoort J Vet Res
December 2024
Natural treatment options for Microsporum canis dermatophytosis are being explored because of resistance to several antifungal medications. In this study, the potential antifungal effect of bee venom (BV), a natural antimicrobial agent, on M. canis was investigated.
View Article and Find Full Text PDFArticle Synopsis
- SCUBE-1 is a new marker indicating ischemia and has been studied for its connection to uteroplacental blood flow in preeclampsia patients.
- In the study, 32 preeclamptic women showed significantly higher maternal serum SCUBE-1 levels compared to a control group of 32 healthy pregnancies, alongside elevated uterine artery pulsatility indexes.
- Although SCUBE-1 levels were higher in preeclampsia, there was no significant correlation with umbilical artery pulsatility index or cerebroplacental ratio, but a notable correlation was found with uterine artery pulsatility index.
Objective: Management of type 1 diabetes (T1DM) is quite challenging for both adolescents and their families. In this study, we aimed to translate the 14-item Problem Areas in Diabetes-Teen (PAID-T) scale, which measures variables that influence diabetes distress, to Turkish and investigate the Turkish version's reliability and validity.
Methods: One hundred and ninety-four adolescents with T1DM participated in the study.
Article Synopsis
- The FLOT 4-AIO trial demonstrated that a docetaxel-based treatment was more effective than an epirubicin-based regimen for patients with locally advanced resectable gastric cancer, but many patients didn't complete the full treatment plan of eight cycles.
- This study compared total neoadjuvant therapy (FLOT x8) with the standard approach (FLOT 4+4) to see which method improved treatment completion and tumor downstaging for patients with advanced gastric tumors prior to surgical removal.
- Results showed that the FLOT x8 group had a significantly higher completion rate of 89.1% compared to 67.6% in the FLOT 4+4