Publications by authors named "S Zawadynski"
Osteoporosis is a bone disorder characterized by bone loss and decreased bone strength. The most widely used technique for detection of osteoporosis is the measurement of bone mineral density (BMD) using dual energy X-ray absorptiometry (DXA). But DXA scans are expensive and not widely available in low-income economies.
View Article and Find Full Text PDFUnlabelled: We propose an automated low cost tool for early diagnosis of onset of osteoporosis using cortical radiogrammetry and cancellous texture analysis from hand and wrist radiographs. The trained classifier model gives a good performance accuracy in classifying between healthy and low bone mass subjects.
Introduction: We propose a low cost automated diagnostic tool for early diagnosis of reduction in bone mass using cortical radiogrammetry and cancellous texture analysis of hand and wrist radiographs.
Article Synopsis
- Young patients with inflammatory bowel disease (IBD) experience reduced bone mineral density (aBMD) and altered bone structure, which increase their risk of fractures.
- A study of 102 individuals showed that those with IBD had lower bone density at various sites and experienced clinical fractures, particularly in the forearm and vertebrae.
- The findings suggest that the changes in bone microarchitecture are linked to the severity of the disease and may lead to a higher likelihood of fragility fractures later in life.
Background: Lipodystrophy (LD) is a frequent adverse event of combination antiretroviral therapy (ART) and occurs mainly in patients exposed to first-generation antiretroviral drugs. The aim of this study was to explore and measure the interaction between LD, mental health, and quality of life of human immunodeficiency virus (HIV) positive individuals seen in a metabolic clinic.
Methods: We conducted a single-site cross-sectional study including all HIV-infected patients attending the LIPO group and metabolism day clinic at the University Hospitals of Geneva, Switzerland between January 31, 2008 and November 28, 2013.
Unlabelled: Glucocorticosteroids (GCs) are the first-line treatment for idiopathic nephrotic syndrome (NS), but prolonged administration interferes with growth and bone mineralization. We conducted a retrospective study to analyze the long-term impact of prednisone on growth and bone mineral density (BMD) in children with NS. Data from children with NS followed during almost 10 years were analyzed.
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